Results 131 to 140 of about 22,179,291 (307)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

All-Cause Mortality and Liver-Related Outcomes Following Successful Antiviral Treatment for Chronic Hepatitis C [PDF]

, 2014
BACKGROUND: Antiviral therapy for the hepatitis C virus (HCV) reduces all-cause and liver-related morbidity and mortality. Few studies are available from populations with multiple medical and psychiatric comorbidities where the impact of successful ...
Colton, Samuel, Thuras, Paul, Pocha, Christine, Knott, Astrid, Ho, Samuel B., Dieperink, Eric   +5 more
core   +2 more sources

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Relationship between the advanced lung cancer inflammation index (ALI) and all-cause and cause-specific mortality among patients with chronic obstructive pulmonary disease (COPD): a population-based study

BMC Pulmonary Medicine
Background Chronic obstructive pulmonary disease (COPD) is viewed as a significant health problem, and the prognosis of patients with this disease is strongly influenced by the inflammatory response and nutritional well-being of the body.
Zhuanbo Luo, Peixu Chen, Luting Chen, Hongying Ma, Chao Cao   +4 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Association of physical activity level and all-cause mortality among stroke survivors: evidence from NHANES 2007–2018

Environmental Health and Preventive Medicine
Background: Post-stroke disability diminishes the physical activity (PA) level of survivors, potentially affecting their long-term prognosis. This study endeavors to explore the correlation between daily PA level and the all-cause mortality in patients ...
Fude Liu, Xiangning Han, Yawen Cheng, Ning Zhu, Shiliang Jiang, Jiahao Li, Jin Zhao, Guogang Luo   +7 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Are Alcohol Excise Taxes Good For Us? Short and Long-Term Effects on Mortality Rates [PDF]

Regression results from a 30-year panel of the state-level data indicate that changes in alcohol-excise taxes cause a reduction in drinking and lower all-cause mortality in the short run.
Philip J. Cook, Frank A. Sloan, Jan Ostermann   +2 more
core  

5-year all-cause mortality.

, 2016
5-year all-cause mortality.
Eric Rullman (431033), Michael Melin (2602570), Thomas Gustafsson (392640), Adrian Gonon (2602567), Inger Hagerman (2602573)   +4 more
core   +1 more source

Sarcopenia Associated with All-Cause Mortality Risk

Journal of the College of Physicians and Surgeons Pakistan
To examine the association of sarcopenia with elevated all-cause mortality risk.Descriptive study. Place and Duration of the Study: Department of Endocrinology, the First College of Clinical Medical Science, China Three Gorges University, Yichang Central People's Hospital, Hubei, China, from December 2024 to April 2025.Data were obtained from 11,176 ...
Shuping, Zhang, Zhaoyang, Zeng
openaire   +2 more sources