Results 101 to 110 of about 16,019,830 (296)
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source
Bragg grating based integrated photonic Hilbert transformers
Planar Bragg grating based photonic Hilbert transformers are experimentally demonstrated in this work. Planar Bragg gratings are utilized to implement a general Hilbert transform, a fractional order Hilbert transform and terahertz bandwidth Hilbert ...
Smith, P.G.R. +7 more
core +2 more sources
All-Pass Filters in Current Mode
Analogue first, second and high-order all-pass active filters in thecurrent mode, with constant group delay and magnitude responses, arepresented in this paper. These filters are based on a modification ofthe multi-loop feedback canonical structures using signal flow graphs.Implementations by multi-output transconductors, namely classical OTAsand novel
openaire +2 more sources
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source
CMOS RF first-order all-pass filter
In this paper, a wide-band first-order voltage-mode all-pass filter is presented. Due to a simple structure and appropriate performance of the proposed all-pass filter, this filter achieves a flat group delay of over 60 ps with a pole/zero pair located ...
Alarcón Cot, Eduardo José +3 more
core
Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias +3 more
wiley +1 more source
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu +7 more
wiley +1 more source
Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella +5 more
wiley +1 more source

