Structural Evidence of a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism [PDF]
, 2018 The X-ray crystal structure of the dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase from Haemophilus influenzae (HiDapE) bound by the products of hydrolysis, succinic acid and l,l-DAP, was determined at 1.95 Å.
Becker, Daniel P. +9 more
core +1 more source
Genome-wide survey of yeast mutations leading to activation of the yeast cell integrity MAPK pathway: Novel insights into diverse MAPK outcomes [PDF]
, 2011 Background The yeast cell wall integrity mitogen-activated protein kinase (CWI-MAPK) pathway is the main regulator of adaptation responses to cell wall stress in yeast.
Patricia Arias +5 more
core +1 more source
New Phytologist, Volume 242, Issue 3, Page 881-902, May 2024.Summary In this review, we untangle the physiological key functions of the essential micronutrients and link them to the deficiency responses in plants. Knowledge of these responses at the mechanistic level, and the resulting deficiency symptoms, have improved over the last decade and it appears timely to review recent insights for each of them.
Grmay Hailu Lilay +6 more
wiley +1 more source
Plant nucleoside N‐ribohydrolases: riboside binding and role in nitrogen storage mobilization
The Plant Journal, Volume 117, Issue 5, Page 1432-1452, March 2024.Significance Statement Plant nucleoside N‐ribohydrolases (NRHs), studied in low and high plants (moss and maize) recognize and hydrolyze purine, cytokinin, and pyrimidine nucleosides through water interactions with the base as shown by X‐ray crystallography.
Eva Ľuptáková +14 more
wiley +1 more source
TNA4OptFlux : a software tool for the analysis of strain optimization strategies [PDF]
, 2013 BACKGROUND:Rational approaches for Metabolic Engineering (ME) deal with the identification of modifications that improve the microbes' production capabilities of target compounds. One of the major challenges created by strain optimization algorithms used
Cardoso, João +4 more
core +2 more sources
Scientifica, Volume 2024, Issue 1, 2024.Since its discovery, numerous studies have shown the role of the microbiota in well‐being and disease. The gut microbiota represents an essential factor that plays a multidirectional role that affects not just the gut but also other parts of the body, including the brain, endocrine system, humoral system, immune system, and metabolic pathways, as well ...
Emmanuel Henry Ezenabor +3 more
wiley +1 more source
Evolutionary Advantage Conferred by an Eukaryote-to-Eukaryote Gene Transfer Event in Wine Yeasts [PDF]
, 2015 Although an increasing number of horizontal gene transfers have been reported in eukaryotes, experimental evidence for their adaptive value is lacking.
Barrio Esparducer, Eladio +9 more
core +2 more sources
Immobilization of allantoinase for the development of an optical biosensor of oxidative stress states [PDF]
, 2020 Allantoin, the natural end product of purine catabolism in mammals, is non-enzymatically produced from the scavenging of reactive oxygen species through the degradation of uric acid.
Bettati S. +3 more
core +1 more source
Competitividade nodular de estirpes de Bradyrhizobium spp. em cultivares de soja sob diferentes disponibilidades hídricas. [PDF]
, 2014 RESUMO: O objetivo do trabalho foi avaliar a competitividade nodular de estirpes de Bradyrhizobium spp. em cultivares de soja sob diferentes disponibilidades hídricas a campo.
CATTELAN, A. J. +6 more
core
Conversion of Uric Acid into Ammonium in Oil-Degrading Marine Microbial Communities: a Possible Role of Halomonads [PDF]
, 2015 Uric acid is a promising hydrophobic nitrogen source for biostimulation of microbial activities in oil-impacted marine environments. This study investigated metabolic processes and microbial community changes in a series of microcosms using sediment from
Abdel-Fattah, Y.R. +15 more
core +2 more sources