Results 231 to 240 of about 1,121,623 (279)

HLA-DRB1 Allelic Combinations Differentially Shape Dendritic Cell Antigen Presentation Enhanced by Tumour Cell Line Lysate-Pulsing. [PDF]

open access: yesHLA
Lázaro G   +9 more
europepmc   +1 more source

Polysomal Profiling Coupled to Allele-Specific Proteomics Reveals an EIF4H TranSNP Allele Possessing Higher mRNA Translation Potential. [PDF]

open access: yesMol Cell Proteomics
Hamadou MH   +9 more
europepmc   +1 more source

ASAH2 deficiency affects sphingolipid homeostasis and neuromotor control, causing a progressive neurological disorder. [PDF]

open access: yesHGG Adv
Scala M   +10 more
europepmc   +1 more source
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Allelic Exchange

2014
Methods used to understand the function of a gene/protein are one of the hallmarks of modern molecular genetics. The ability to genetically manipulate bacteria has become a fundamental tool in studying these organisms and while basic cloning has become a routine task in molecular biology laboratories, generating directed mutations can be a daunting ...
McKenzie K, Lehman   +2 more
openaire   +2 more sources

Estimating Allele Frequencies

2011
Methods of estimating allele frequencies from data on unrelated and related individuals are described in this chapter. For samples of unrelated individuals with simple codominant markers, the natural estimator of allele frequencies can be used. For genetic data on related individuals, maximum likelihood estimation (MLE) can be applied to compute allele
Indra, Adrianto, Courtney, Montgomery
openaire   +3 more sources

Estimating Allele Age

Annual Review of Genomics and Human Genetics, 2000
The age of an allele can be estimated both from genetic variation among different copies (intra-allelic variation) and from its frequency. Estimates based on intra-allelic variation follow from the exponential decay of linkage disequilibrium because of recombination and mutation.
M, Slatkin, B, Rannala
openaire   +2 more sources

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