Results 261 to 270 of about 1,163,092 (332)

The 5-methylcytosine DNA glycosylase ROS1 prevents paternal genome hypermethylation in Arabidopsis endosperm. [PDF]

Genome Biol
Hemenway EA, Gehring M.
europepmc   +1 more source

THE METASTABLE NATURE OF PARAMUTABLE R ALLELES IN MAIZE. I. HERITABLE ENHANCEMENT IN LEVEL OF STANDARD Rr ACTION

, 1966
E. D. Styles, R. A. Brink
openalex   +2 more sources

Treating Hearing Loss: From Cochlear Implantation to Gene Therapy

Advanced Science, EarlyView.
Cochlear implantation is the primary treatment for deafness, restoring functional hearing in over a million people. Recently, gene therapy has enabled biological hearing restoration in a small number of patients with OTOF‐related mutations. This perspective evaluates both approaches, concluding that cochlear implants will remain the standard for most ...
Fan‐Gang Zeng, Jieyu Qi, Chen‐Chi Wu, Yilai Shu, Renjie Chai   +4 more
wiley   +1 more source

Soluble CTLA-4 and high-risk genetic variants: A new frontier in pancreatic ductal adenocarcinoma (PDAC) biomarkers. [PDF]

Biochem Biophys Rep
Hassan M, Elhusseny Y, Agamy FE, Azmy MM, Balata M.   +4 more
europepmc   +1 more source

EFFECT OF A TRANSLOCATION IN MAIZE ON SENSITIVITY TO PARAMUTATION OF Rr ALLELES FROM THREE GEOGRAPHIC SOURCES

, 1965
R. A. Brink, J. Venkateswarlu
openalex   +2 more sources

CSN6 Promotes Pancreatic Cancer Progression and Gemcitabine Resistance via Antagonizing DCAF1‐Mediated Ubiquitination of NPM1

Advanced Science, EarlyView.
COP9 signalosome subunit 6 (CSN6) promotes the auto‐ubiquitination and degradation of DDB1‐CUL4 associated factor 1 (DCAF1), thereby antagonizing DCAF1‐mediated ubiquitination of Nucleophosmin (NPM1). This stabilization of NPM1 enhances the ribosome biogenesis process and the translation of specific gemcitabine‐resistance proteins, ultimately driving ...
Yijing Zhang, Han Gao, Aiwen Tang, Haiwen Lyu, Zongmin Fan, Jiahui Guo, Yuzhi Wang, Hairong Yi, Qihao Pan, Haidan Luo, Baifu Qin, Boyu Zhang, Xiangqi Meng, Qingxin Liu, Mong‐Hong Lee   +14 more
wiley   +1 more source

Diversity of MHC-B SNP haplotypes in the Vietnamese Ri chicken. [PDF]

J Anim Sci Technol
Nam S, Manjula P, Kim J, Kim M, Cho E, Agulto TN, Hong YH, Lee JH.   +7 more
europepmc   +1 more source

THE SERIAL TRANSPLANTATION OF HAEMATOPOIETIC TISSUE IN MICE WITH THE SAME H-2 ALLELE

, 1966
Ann M. Dresser, D W Dressser
openalex   +1 more source

Uric Acid Functions as an Endogenous Modulator of Microglial Function and Amyloid Clearance in Alzheimer's Disease

Advanced Science, EarlyView.
Higher serum UA levels are associated with reduced AD risk in epidemiological studies. UA enhances microglial phagocytic capacity primarily by restoring CD36 and TREM2 receptor recycling that is impaired by Aβ exposure. Therapeutically, UA supplementation improves cognitive function and reduces neuropathology in AD mouse model by enhancing microglial ...
De Xie, Qiuyang Zheng, Jiaming Lv, Qian Zhang, Zhiwei Cui, Shuai Huang, Wei Yu, Binyang Chen, Wanling Que, Shanpan Fu, Yuemei Xi, Jiayu Chen, Xueling Ye, Shuyi Chen, Hairong Zhao, Tetsuya Yamamoto, Hidenori Koyama, Xin Wang, Jidong Cheng   +18 more
wiley   +1 more source

Survey of functional Mendelian variants in New Zealand Huntaway and Heading dog breeds. [PDF]

Anim Genet
Smith F, Lopdell T, Stephen M, Henry M, Dittmer K, Hunt H, Sneddon N, Williams L, Rolfe J, Garrick D, Littlejohn MD.   +10 more
europepmc   +1 more source