Results 261 to 270 of about 1,408,208 (397)
ALLELE SPECIFIC DETERMINANTS OF HOMOTHALLISM IN SACCHAROMYCES LACTIS [PDF]
A. I. Herman, Herschel Roman
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DPImpute is a two‐step pipeline that outperforms existing tools in whole‐genome SNP imputation, particularly under conditions of ultra‐low coverage sequencing, small sample sizes, and limited references. It enables precise imputation for single blastocyst cells, supporting genomic selection at the pre‐implantation stage.
Weigang Zheng+11 more
wiley +1 more source
Atlas of imprinted and allele-specific DNA methylation in the human body. [PDF]
Rosenski J+7 more
europepmc +1 more source
Instability at the pal locus in Antirrhinum majus II. Multiple alleles produced by mutation of one original unstable allele [PDF]
J. R. S. Fincham, B J Harrison
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This study indicates that Serpine2 plays a pivotal role in hair cell (HC) regeneration from Lgr5+ progenitors in the neonatal mouse cochlea. Conditional overexpression of Serpine2 in cochlear Lgr5+ progenitors results in a significantly increased number of ectopic HCs, particularly ectopic inner HCs, and these HCs are likely derived from Lgr5 ...
Hairong Xiao+14 more
wiley +1 more source
STRchive: a dynamic resource detailing population-level and locus-specific insights at tandem repeat disease loci. [PDF]
Hiatt L+9 more
europepmc +1 more source
This study reveals a novel crosstalk between hepatic SREBP2‐mediated cholesterol biosynthesis pathway and peripheral lipoprotein lipase‐mediated lipolysis pathway in the regulation of systemic lipid metabolism. Notably, the lipid‐lowering effects of SREBP2 inhibition are independent of a functional LDL receptor, highlighting the potential of acute ...
Yifan Wang+13 more
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Allele co-segregation and haplotype diversity of MHC IIβ genes in the small-spotted catshark Scyliorhinus canicula. [PDF]
Rota A, Veríssimo A, Gaigher A.
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Genomic Insights into Post‐Domestication Expansion and Selection of Body Size in Ponies
The authors’ research delves into the history of ponies by assembling a pony genome and integrating horse genomes. This unveils genetic connections between Asian and European pony breeds. Cis‐regulatory elements of key genes impacting body size are also identified.
Xingzheng Li+23 more
wiley +1 more source