Results 41 to 50 of about 5,316,209 (336)

Evidence for selection on SARS-CoV-2 RNA translation revealed by the evolutionary dynamics of mutations in UTRs and CDSs

open access: yesRNA Biology, 2022
RNA translation is the rate-limiting step when cells synthesize proteins. Elevating translation efficiency (TE) is intuitively beneficial. Particularly, when viruses invade host cells, how to compete with endogenous RNAs for efficient translation is a ...
Lin Zhu   +4 more
doaj   +1 more source

Minor allele frequency thresholds dramatically affect population structure inference with genomic datasets

open access: yesbioRxiv, 2017
One common method of minimizing errors in large DNA sequence datasets is to drop variable sites with a minor allele frequency below some specified threshold.
E. Linck, C. Battey
semanticscholar   +1 more source

Use of Microsatellites in Genetic Diversity Assessment, Parentage Testing and Individual Identification of the Kangal Shepherd Dog

open access: yesActa Veterinaria, 2020
The Kangal Shepherd Dog is considered the most common dog breed of Turkish origin. This study investigated variations in ten autosomal microsatellite markers (PEZ01, PEZ03, PEZ05, PEZ06, PEZ08, PEZ12, PEZ20, FHC2010, FHC2054 and FHC2079) for the purposes
Vladimir Dimitrijević   +6 more
doaj   +1 more source

ALLELE FREQUENCIES IN MULTIGENE FAMILIES [PDF]

open access: yesJournal of the Indonesian Mathematical Society, 2012
Results on allelle frequencies in three chromosomes, drawn at randomfrom a diploid population, evolving in equilibrium, at a particular generation, arepresented in this paper. The genes on each chromosome are subject to unbiased andreciprocal gene conversion and mutation.
openaire   +2 more sources

A Bayesian hierarchical model for allele frequencies [PDF]

open access: yesGenetic Epidemiology, 2000
Genetic epidemiological methodologies, such as linkage analysis, often require accurate estimates of allele frequencies. When studies involve multiple sub-populations with different evolutionary histories, accurate estimates can be difficult to obtain because the number of subjects per sub-population tends to be limited.
Kathryn Roeder   +2 more
openaire   +3 more sources

Heterogenous Distribution of MTHFR Gene Variants among Mestizos and Diverse Amerindian Groups from Mexico. [PDF]

open access: yesPLoS ONE, 2016
Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in folate metabolism. Folate deficiency has been related to several conditions, including neural tube defects (NTDs) and cardiovascular diseases.
Cecilia Contreras-Cubas   +15 more
doaj   +1 more source

THE REAL McCOIL: A method for the concurrent estimation of the complexity of infection and SNP allele frequency for malaria parasites

open access: yesPLoS Comput. Biol., 2017
As many malaria-endemic countries move towards elimination of Plasmodium falciparum, the most virulent human malaria parasite, effective tools for monitoring malaria epidemiology are urgent priorities. P.
Hsiao-Han Chang   +15 more
semanticscholar   +1 more source

Allelic variants of breast cancer susceptibility genes PALB2 and RECQL in the Latvian population

open access: yesHereditary Cancer in Clinical Practice, 2019
Background Large-scale case control studies revealed a number of moderate risk - low frequency breast cancer alleles of the PALB2 and RECQL genes. Some of these were reported as founder variants of Central and Eastern Europe.
Philip Hilz   +9 more
doaj   +1 more source

Systematic pan-cancer analysis of somatic allele frequency

open access: yesScientific Reports, 2018
Imbalanced expression of somatic alleles in cancer can suggest functional and selective features, and can therefore indicate possible driving potential of the underlying genetic variants.
Liam F. Spurr   +11 more
semanticscholar   +1 more source

V-leaf marking in a Trifolium ambiguum Bieb. germplasm collection

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca, 1987
Frequency values have been registered in the neomorph multiple allele series of V-leaf marking in a germplasm collection of Caucasian (Kura) clover - Trifolium ambiguum Bieb. This collection, obtained from the Northwest Reg. Plant Instr. Stn., Geneva N.Y.
Attila T. SZABO
doaj   +1 more source

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