Results 91 to 100 of about 891,020 (314)

Occurrence of Alleles of the HLA-A/B/C/DPB1/DQB1/DRB1 Genes in Autoimmune Hepatitis (Results of a Single-Center Study)

Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: determination of alleles of HLA genes associated with autoimmune hepatitis (AIH) and overlap syndrome (OS) in the Russian population.Materials and methods. The study included 160 adult patients with a verified diagnosis of AIH or OS.
M. D. Chanyshev, Yu. G. Sandler, N. V. Vlasenko, N. A. Bodunova, A. G. Glushchenko, A. S. Chegodar, A. V. Vykhodtseva, E. V. Vinnitskaya, K. F. Khafizov, V. G. Akimkin   +9 more
doaj   +1 more source

Correction: A novel hypomorphic allele of Spag17 causes primary ciliary dyskinesia phenotypes in mice [PDF]

, 2021
Zakia Abdelhamed, Marshall Lukacs, Sandra Cindrić, Saima Ali, Heymut Omran, Rolf W. Stottmann   +5 more
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Variability of omp25 and omp2a Genes in Brucella Strains of Different Taxonomic Position

Проблемы особо опасных инфекций
The aim of the study was to identify structural differences in the Brucella omp25 and omp2a genes, which make it possible to determine their taxonomic position.Materials and methods.
N. A. Osina, E. G. Boolgakova, A. G. Osin, I. G. Shvidenko, S. A. Shcherbakova   +4 more
doaj   +1 more source

Genetic variability of 10 microsatellite markers in the characterization of Brazilian Nellore cattle (Bos indicus)

Genetics and Molecular Biology, 2006
We assessed the polymorphism of 10 microsatellites in Brazilian Nellore cattle (Bos indicus) using a commercial multiplex system. Allele frequencies, polymorphism information content, heterozygosity and exclusion probability were calculated.
Marcelo Cervini, Flávio Henrique-Silva, Norma Mortari, Euclides Matheucci Jr   +3 more
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Application of SSR markers for assessment of genetic similarity and genotype identification in local winter wheat breeding program

Біологічні студії
Background. Simple sequence repeat (SSR) markers are widely used for genetic analysis in plant breeding, allowing for the investigation of genetic divergence and similarity of genotypes, identification of unique alleles and determination of levels of ...
Mariia Batashova, Liudmyla Kryvoruchko, Bohdana Makaova-Melamud, Volodymyr Tyshchenko, Martin Spanoghe   +4 more
doaj   +1 more source

Expression of natural killer receptor alleles at different Ly49 loci occurs independently and is regulated by major histocompatibility complex class I molecules. [PDF]

, 2001
Ly49 receptor genes are expressed by subsets of natural killer (NK) cells in an overlapping fashion, accounting for the capacity of NK subsets to attack host cells that have selectively downregulated self-major histocompatibility complex (MHC) class I ...
Hanke, T, Jamieson, A, RAULET, David H., Takizawa, H, Tanamachi, D   +4 more
core   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Allele [PDF]

, 2011
  +7 more sources