Results 91 to 100 of about 881,725 (335)

The evolution of moment generating functions for the Wright Fisher model of population genetics

, 2014
We derive and apply a partial differential equation for the moment generating function of the Wright-Fisher model of population ...
Hofrichter, Julian, Jost, Juergen, Tran, Tat Dat   +2 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

The influence of allelic variants of the Vrn-A1 gene on the duration of the vegetation period in Triticum dicoccoides

Вавиловский журнал генетики и селекции
The duration of the vegetation period (DVP) is an important agronomic trait in cereal. Тhe main influence on it in wheat is exerted by Vrn genes, which determine the growth habit (spring vs. winter) and DVP.
G. Yu. Chepurnov, Z. Chen, A. G. Blinov, V. M. Efimov, N. P. Goncharov   +4 more
doaj   +1 more source

PRC1 wt Allele [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

Laboratory colonisation and genetic bottlenecks in the tsetse fly Glossina pallidipes [PDF]

, 2014
Background The IAEA colony is the only one available for mass rearing of Glossina pallidipes, a vector of human and animal African trypanosomiasis in eastern Africa. This colony is the source for Sterile Insect Technique (SIT) programs in East Africa.
Ciosi, Marc, Masiga, Daniel K., Turner, Charles M.R.   +2 more
core   +3 more sources

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

BIRC5 wt Allele [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

First multi-locus sequence typing scheme for Arcobacter spp. [PDF]

, 2009
Background: Arcobacter spp. are a common contaminant of food and water, and some species, primarily A. butzleri and A. cryaerophilus, have been isolated increasingly from human diarrheal stool samples.
Miller, William G, Wesley, Irene V, On, Stephen LW, Houf, Kurt, Megraud, Francis, Wang, Guilin, Yee, Emma, Srijan, Apichai, Mason, Carl J   +8 more
core   +3 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source