Results 141 to 150 of about 870,271 (337)

Copper Stress Response of Antibiotic‐Resistant and Copper‐Tolerant Enterococcus faecium and the Antibacterial Efficacy of Functionalized Copper Surfaces

open access: yesAdvanced Materials Interfaces, EarlyView.
This study examines how different laser‐patterned copper and brass surfaces, including copper coatings, affect the survival of vancomycin‐resistant Enterococcus faecium. Using microscopy and genome analysis, the results show that copper tolerance varies between strains and can increase after vancomycin exposure.
Franca Arndt   +18 more
wiley   +1 more source

Precision Diagnostics in Sports‐Related Traumatic Brain Injury: Pathophysiology, Biomarker Development and Emerging Technologies

open access: yesAdvanced Sensor Research, EarlyView.
Sports‐related traumatic brain injuries (TBIs) remain underdiagnosed, within amateur athletic cohorts. This review critically synthesises recent advancements in AI‐assisted neuroimaging, blood‐based biomarker profiling, wearable biosensing platforms for early detection, injury stratification, and longitudinal surveillance of TBIs.
Daniel Nicol   +3 more
wiley   +1 more source

Variability of omp25 and omp2a Genes in Brucella Strains of Different Taxonomic Position

open access: yesПроблемы особо опасных инфекций
The aim of the study was to identify structural differences in the Brucella omp25 and omp2a genes, which make it possible to determine their taxonomic position.Materials and methods.
N. A. Osina   +4 more
doaj   +1 more source

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

open access: yesAdvanced Science, EarlyView.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang   +15 more
wiley   +1 more source

KIF5A p.Pro986Leu Risk Variant and Accelerated Progression of Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology
This study explored the impact of KIF5A rs113247976 (p.Pro986Leu), a risk allele for amyotrophic lateral sclerosis (ALS), on phenotypic variability in two Italian ALS cohorts (discovery, n = 865; replication, n = 1174). The minor allele (T) frequency was
Arianna Manini   +24 more
doaj   +1 more source

Occurrence of Alleles of the HLA-A/B/C/DPB1/DQB1/DRB1 Genes in Autoimmune Hepatitis (Results of a Single-Center Study)

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: determination of alleles of HLA genes associated with autoimmune hepatitis (AIH) and overlap syndrome (OS) in the Russian population.Materials and methods. The study included 160 adult patients with a verified diagnosis of AIH or OS.
M. D. Chanyshev   +9 more
doaj   +1 more source

CRISPR‐MI and scRNA‐Seq Reveal TREM2's Function in Monocyte Infiltration and Macrophage Apoptosis During Abdominal Aortic Aneurysm Development

open access: yesAdvanced Science, EarlyView.
A method is developed for conducting genome‐wide CRISPR/Cas9 screening of monocyte infiltration in vivo (CRISPR‐MI) that is easily adaptable across a variety of disease models. Through the combination of CRISPR‐MI and scRNA‐Seq, this study discovers that Trem2 is a key regulator of early monocyte infiltration in abdominal aortic aneurysm (AAA ...
Haocheng Lu   +30 more
wiley   +1 more source

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