Results 181 to 190 of about 891,020 (314)

Gene Flooding: Proposal to Flood Invasive Populations With Inbred Individuals as a Form of Low-Tech Genetic Control. [PDF]

Ecol Evol
Gould J, Beranek C.
europepmc   +1 more source

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source

Sex-Specific doublesex Regulation Targeting the Color-Patterning Gene h Underlies the Evolution of Wing Sexual Dimorphism in the Harlequin Ladybug Harmonia axyridis. [PDF]

Evol Dev
Yeki S, Kato K, Morita S, Shimomura K, Niimi T, Hinomoto N, Daimon T, Ando T.   +7 more
europepmc   +1 more source

Variation for heterodimerization and nuclear localization among known and novel oil palm SHELL alleles [PDF]

, 2019
Rajinder Singh, Eng‐Ti Leslie Low, Leslie Cheng‐Li Ooi, Meilina Ong‐Abdullah, Ngoot‐Chin Ting, N. Rajanaidu, Maizura Ithnin, Marhalil Marjuni, Suzana Mustaffa, Zulkifli Yaakub, Mohd Din Amiruddin, Mohamad Arif Abdul Manaf, Kuang‐Lim Chan, Mohd Amin Ab Halim, Nik Shazana Nik Mohd Sanusi, Nathan Lakey, Mohit Sachdeva, Blaire Bacher, Peggy A. Garner, Jill D. MacDonald, Steven W. Smith, Corey Wischmeyer, Muhammad A. Budiman, Melissa Beil, Clayton Stroff, Jerry P. Reed, Andrew Van Brunt, R. Howard Berg, Jared M. Ordway, Ravigadevi Sambanthamurthi   +29 more
openalex   +1 more source

Domestication of Tartary Buckwheat Shaped a Regulatory Module for Seedling Salt Tolerance by Targeting the Magnesium Transporter Gene FtMGT2

Advanced Science, EarlyView.
Domestication of Tartary buckwheat is selected for a salt tolerance mechanism involving the magnesium transporter FtMGT2. Its expression is controlled by the FtAGL16‐FtMYB15L module, which is stabilized under salt stress through a competitive interaction that blocks its degradation by the E3 ligase FtBRG1, ultimately boosting Na⁺ efflux and plant ...
Xiang Lu, Yuqi He, Wenfeng Weng, Zebin Liu, Yuanfen Gao, Yaliang Shi, Wei Li, Dili Lai, Mengyu Zhao, Rintu Jha, Hui Zhao, Guangsheng Li, Chaonan Guan, Shuai Shao, Jingjun Ruan, Sun Hee Woo, Yinan Ouyang, Muriel Quinet, Milen I. Georgiev, Alisdair R. Fernie, Congcong Hou, Kaixuan Zhang, Xu Liu, Meiliang Zhou   +23 more
wiley   +1 more source

Important role in transcription start site selection for the RNA polymerase II-TFIIE-TFIIH interface in Saccharomyces cerevisiae. [PDF]

Genetics
Basnet P, Zhu Y, Vvedenskaya IO, Arora P, Hammer S, McVicar B, Alex S, Nickels BE, Kaplan CD.   +8 more
europepmc   +1 more source

Cerebrospinal fluid-induced retardation of amyloid β aggregation correlates with Alzheimer's disease and the APOE ε4 allele

, 2016
Eden Padayachee, Henrik Zetterberg, Erik Portelius, Jan Borén, José Luís Molinuevo, Nancy C. Andreasen, Risto Cukalevski, Sara Linse, Kaj Blennow, Ulf Andréasson   +9 more
openalex   +1 more source

Gorilla class I major histocompatibility complex alleles: comparison to human and chimpanzee class I. [PDF]

, 1991
Debbie A. Lawlor, Ean Warren, Philip L. Taylor, Peter Parham   +3 more
openalex   +1 more source

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance

Advanced Science, EarlyView.
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar, Vishwa I. P. W. A. Kumara, Pradeepa C. G. Bandaranayake, Dong Yawen, Yang‐Yang Gao, Junfeng Liu, Ge‐Fei Hao, Xiu‐Fang Xin   +7 more
wiley   +1 more source

Mapping Allele-Specific DNA Methylation: A New Tool for Maximizing Information from GWAS [PDF]

, 2010
Benjamin Tycko
openalex   +1 more source