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Estimating Allele Frequencies

2011
Methods of estimating allele frequencies from data on unrelated and related individuals are described in this chapter. For samples of unrelated individuals with simple codominant markers, the natural estimator of allele frequencies can be used. For genetic data on related individuals, maximum likelihood estimation (MLE) can be applied to compute allele
Indra, Adrianto, Courtney, Montgomery
openaire   +3 more sources

Asymptotics of the allele frequency spectrum and the number of alleles

Journal of Applied Probability
AbstractWe derive large-sample and other limiting distributions of components of the allele frequency spectrum vector, $\mathbf{M}_n$ , joint with the number of alleles, $K_n$ , from a sample of n genes. Models analysed include those constructed from gamma and $\alpha$ -stable subordinators by Kingman (thus including the Ewens model), the two ...
Ross Maller, Soudabeh Shemehsavar
openaire   +1 more source

On the Genealogy of a Rare Allele

Theoretical Population Biology, 1997
The gene genealogy is derived for a rare allele that is descended from a mutant ancestor that arose at a fixed time in the past. Following Thompson (1976, Amer. J. Human Genet. 28, 442-452), the fractional linear branching process is used as a model of the demography of a rare allele.
openaire   +2 more sources

Hybrid speciation via inheritance of alternate alleles of parental isolating genes

Molecular Plant, 2021
Quanjun Hu   +2 more
exaly  

Allele

2012
Dieter Böning   +46 more
  +4 more sources

Alleles

2021
openaire   +1 more source

Microsatellite Null Alleles and Estimation of Population Differentiation

Molecular Biology and Evolution, 2007
Arnaud Estoup   +2 more
exaly  

NK3-specific natural killer cells are selectively inhibited by Bw4-positive HLA alleles with isoleucine 80.

Journal of Experimental Medicine, 1994
Colonna M, Ferrara G B, Strominger J L
exaly  

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