Results 21 to 30 of about 880,277 (345)

High-Resolution Characterization of KIR Genes in a Large North American Cohort Reveals Novel Details of Structural and Sequence Diversity

open access: yesFrontiers in Immunology, 2021
The KIR (killer-cell immunoglobulin-like receptor) region is characterized by structural variation and high sequence similarity among genes, imposing technical difficulties for analysis.
Leonardo M. Amorim   +13 more
doaj   +1 more source

Novel alleles of rice eIF4G generated by CRISPR/Cas9‐targeted mutagenesis confer resistance to Rice tungro spherical virus

open access: yesPlant Biotechnology Journal, 2018
Summary Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between Rice tungro spherical virus (RTSV) and Rice tungro bacilliform virus.
A. Macovei   +8 more
semanticscholar   +1 more source

Genetic variability of 10 microsatellite markers in the characterization of Brazilian Nellore cattle (Bos indicus)

open access: yesGenetics and Molecular Biology, 2006
We assessed the polymorphism of 10 microsatellites in Brazilian Nellore cattle (Bos indicus) using a commercial multiplex system. Allele frequencies, polymorphism information content, heterozygosity and exclusion probability were calculated.
Marcelo Cervini   +3 more
doaj   +1 more source

Genotypic stratification of risk of acute cerebral circulation disorder

open access: yesКардиоСоматика, 2021
Aim. To study the association of rs662799 gene APOA5 with the development of Acute Cerebrovascular Event in patients with cardiovascular diseases (CVD) and their risk factors. Material and methods. 260 Acute Cerebrovascular Event patients (main group)
Dmitriy A. Nikulin   +4 more
doaj   +1 more source

Application of EST-SSR markers for analysis of polymorphism of lettuce varieties (Lactuca sativa L.) of domestic breeding

open access: yesPlant Varieties Studying and Protection, 2020
Purpose. Determination of molecular genetic polymorphism of lettuce cultivars of Ukrainian breeding by EST-SSR markers. Methods. Molecular genetic analysis, statistical methods. Results.
Н. В. Лещук   +4 more
doaj   +1 more source

Beta-lactoglobulin (BLG) gene polymorphism in Ukrainian and foreign cows

open access: yesБіологія тварин, 2021
The aim of the study was to study the polymorphism of the beta-lactoglobulin gene in cows of Ukrainian Red-Spotted dairy cattle and Montbéliarde breeds and animals obtained by crossing the local Ukrainian Red-Spotted dairy cattle with bulls of ...
I. Mitioglo
doaj   +1 more source

Variant ribosomal RNA alleles are conserved and exhibit tissue-specific expression

open access: yesScience Advances, 2018
Ribosomal RNA sequence variants are conserved, exhibit tissue-specific expression, and are found in actively translating ribosomes. The ribosome, the integration point for protein synthesis in the cell, is conventionally considered a homogeneous ...
Matthew M. Parks   +10 more
semanticscholar   +1 more source

Mosaicism in Vacuolating Cytotoxin Alleles of Helicobacter pylori

open access: yesJournal of Biological Chemistry, 1995
Approximately 50% of Helicobacter pylori strains produce a cytotoxin, encoded by vacA, that induces vacuolation of eukaryotic cells. Analysis of a clinically isolated tox strain (Tx30a) indicated secretion of a 93-kDa product from a 3933-base pair vacA ...
J. Atherton   +5 more
semanticscholar   +1 more source

Allele age and a test for selection on rare alleles [PDF]

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2000
An approximate expression for the probability distribution of the age of a neutral allele as a function of its frequency is derived for a population undergoing arbitrary changes in population size. A simple maximum–likelihood estimator of allele age based on frequency is also obtained.
openaire   +3 more sources

Risk alleles for multiple sclerosis identified by a genomewide study.

open access: yesNew England Journal of Medicine, 2007
BACKGROUND Multiple sclerosis has a clinically significant heritable component. We conducted a genomewide association study to identify alleles associated with the risk of multiple sclerosis. METHODS We used DNA microarray technology to identify common
D. Hafler   +18 more
semanticscholar   +1 more source

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