Results 301 to 310 of about 870,271 (337)

Changes in allele frequency [PDF]

, 2012
Liu, Huiming, Berg, Peer, Sørensen, Anders Christian, Norberg, Elise   +3 more
openaire   +1 more source

Massively parallel immunopeptidome by DNA sequencing provides insights into cancer antigen presentation. [PDF]

Nat Genet
Shi Q, Simon EP, Cimen Bozkus C, Kaminska A, Velazquez L, Saxena M, Zhang Z, Belk JA, Wang S, Yang N, Zhang Y, Kwong A, Che Y, Stickels RR, Crain CR, Schmidt-Hong L, Lichti CF, Gaiha GD, Roth TL, Bhardwaj N, Satpathy AT, Yu B, Chang HY.   +22 more
europepmc   +1 more source

From Photoperiod Thresholds to Photoperiod sensitivity: Dual Strategies for Cost-Effective Speed Breeding and Climate-Ready Barley

Rossi N, Powell W, Halliday K, Sharma R.
europepmc   +1 more source

Comment on “Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease”

Advanced Science, EarlyView.
Hongye Peng, Shaojie Duan
wiley   +1 more source

Mating of Alleles [PDF]

, 1994
Genetic theory is used in two basic commercial ways today: animal and plant breeding in agriculture and in the field of conservation biology. In the former, the basic strategy is to identify and eliminate undesirable, susceptible alleles by selective breeding. The susceptibility can be to a particular disease or perhaps it is manifested as a structural
Bruce Hannon, Matthias Ruth
openaire   +1 more source

Estimating Allele Frequencies [PDF]

, 2011
Methods of estimating allele frequencies from data on unrelated and related individuals are described in this chapter. For samples of unrelated individuals with simple codominant markers, the natural estimator of allele frequencies can be used. For genetic data on related individuals, maximum likelihood estimation (MLE) can be applied to compute allele
Indra Adrianto, Courtney G. Montgomery
openaire   +3 more sources

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The Missing ApoE Allele

Annals of Human Genetics, 2007
SummaryThe human apoE gene (APOE, GenBank accession AF261279) shows a common polymorphism, with the three ɛ2, ɛ3 and ɛ4 alleles resulting from the haplotypes of two C→T SNPs. However, whereas the three common T‐T, T‐C and C‐C haplotypes corresponding to the ɛ2, ɛ3 and ɛ4 alleles are well known, the last C‐T haplotype (GenBank accession AY077451 ...
Antonio Daniele, Davide Seripa, L. Bisceglia, Monica Rinaldi, G. Dal Forno, Maria Giovanna Matera, Carlo Masullo, Vincenzo Solfrizzi, R. M. Corbo, Carolina Gravina, Andrea Pilotto, Francesco Panza, Alessandra Bizzarro, Vito Michele Fazio, Vito Michele Fazio, Bruno Dallapiccola   +15 more
openaire   +7 more sources

The distribution of rare alleles

Journal of Mathematical Biology, 1995
Population geneticists have long been interested in the behavior of rare variants. The definition of a rare variant has been the subject of some debate, centered mainly on whether alleles with small relative frequency should be considered rare, or whether alleles with small numbers should be.
Simon Tavaré, Paul Joyce
openaire   +3 more sources

ALLELISM, NON-ALLELISM, AND GENETIC COMPOUNDS AMONG THE MUCOPOLYSACCHARIDOSES

The Lancet, 1972
Abstract On the basis of cellular studies it is proposed that the genes for the strikingly dissimilar Hurler and Scheie syndromes are allelic, and that genetic compounds of the Hurler and Scheie genes occur, presenting an intermediate phenotype. Two clinically distinct forms of X-linked mucopolysaccharidosis (Hunter syndrome) are probably determined ...
Victor A. McKUSICK, Victor A. McKUSICK, Irene E. Hussels, Irene E. Hussels, Elizabeth F. Neufeld, Elizabeth F. Neufeld, Roger E. Stevenson, Roger E. Stevenson, R. Rodney Howell, R. Rodney Howell   +9 more
openaire   +3 more sources

Allelic histories: positive selection on a HIV-resistance allele

Trends in Ecology & Evolution, 2004
The CCR5-Delta32 allele crucially determines the course of HIV infection and appears to be highly protective against the disease. Population genetic studies suggest that the allele has been under positive selection in Europe in the past. In a recent paper, Alison Galvani and Montgomery Slatkin collate the available evidence and use a mathematical model
Hilde Wilkinson-Herbots, Michael P. H. Stumpf   +1 more
openaire   +3 more sources