Results 301 to 310 of about 880,277 (345)

HLA common and well‐documented alleles in China

HLA, 2018
The American Society for Histocompatibility and Immunogenetics HLA common and well‐documented (CWD) catalog, CWD 2.0.0 catalog and European Federation for Immunogenetics (EFI) CWD catalog have been published, which are useful for improving the accuracy ...
Y. He, J. Li, W. Mao, D. Zhang, M. Liu, X. Shan, B. Zhang, C. Zhu, J. Shen, Z. Deng, Z. Wang, W. Yu, Q. Chen, W. Guo, P. Su, R. Lv, G. Li, G. Li, B. Pei, L. Jiao, G. Shen, Y. Liu, Z. Feng, Y. Su, Y. Xie, W. Di, X. Liu, X. Yang, J. Wang, J. Qi, Q. Liu, Y. Han, J. He, J. Cai, Z. Zhang, F. Zhu, D. Du   +36 more
semanticscholar   +1 more source

ALLELISM, NON-ALLELISM, AND GENETIC COMPOUNDS AMONG THE MUCOPOLYSACCHARIDOSES

The Lancet, 1972
Abstract On the basis of cellular studies it is proposed that the genes for the strikingly dissimilar Hurler and Scheie syndromes are allelic, and that genetic compounds of the Hurler and Scheie genes occur, presenting an intermediate phenotype. Two clinically distinct forms of X-linked mucopolysaccharidosis (Hunter syndrome) are probably determined ...
Victor A. McKUSICK, Victor A. McKUSICK, Irene E. Hussels, Irene E. Hussels, Elizabeth F. Neufeld, Elizabeth F. Neufeld, Roger E. Stevenson, Roger E. Stevenson, R. Rodney Howell, R. Rodney Howell   +9 more
openaire   +3 more sources

Allelic histories: positive selection on a HIV-resistance allele

Trends in Ecology & Evolution, 2004
The CCR5-Delta32 allele crucially determines the course of HIV infection and appears to be highly protective against the disease. Population genetic studies suggest that the allele has been under positive selection in Europe in the past. In a recent paper, Alison Galvani and Montgomery Slatkin collate the available evidence and use a mathematical model
Hilde Wilkinson-Herbots, Michael P. H. Stumpf   +1 more
openaire   +3 more sources

The use marker alleles for the introgression of linked quantitative alleles

Theoretical and Applied Genetics, 1977
It is shown that when an exotic strain and a commercial strain differ genetically at a quantitative locus and at an adjoining marker locus, repeated backcrosses to the commercial strain, retaining only backcross progeny carrying the exotic marker allele, will allow the effective introgression of the linked quantitative allele from the exotic to the ...
J. Plotkin-Hazan, M. Soller
openaire   +3 more sources

Allelic Exchange

2014
Methods used to understand the function of a gene/protein are one of the hallmarks of modern molecular genetics. The ability to genetically manipulate bacteria has become a fundamental tool in studying these organisms and while basic cloning has become a routine task in molecular biology laboratories, generating directed mutations can be a daunting ...
McKenzie K, Lehman, Jeffrey L, Bose, Kenneth W, Bayles   +2 more
openaire   +2 more sources

Frequency of Gc Alleles and a Variant Gc Allele in Iceland

Human Heredity, 1980
The gene frequency for Gc1 and Gc2 in an Icelandic population was found to be 0.71 and 0.29, respectively. An electrophoretic variant similar to Gc Norway was detected in 5 individuals of the same family. A pedigree of 14 family members, including two spouses, is presented.
Gudmundur Thordarson, Stefan Karlsson, Bjørnar Olaisen, Alfred Arnason   +3 more
openaire   +3 more sources

Rare Alleles and Selection

Theoretical Population Biology, 2001
A subpopulation D of rare alleles is considered. The subpopulation is part of a large population that evolves according to a Moran model with selection and growth. Conditional on the current frequency, q, of the rare allele, an approximation to the distribution of the genealogy of D is derived.
openaire   +4 more sources

Simultaneous estimation of null alleles and inbreeding coefficients.

Journal of Heredity, 2009
Although microsatellites are a very efficient tool for many population genetics applications, they may occasionally produce "null" alleles, which, when present in high proportion, may affect estimates of key parameters such as inbreeding and relatedness ...
I. Chybicki, J. Burczyk
semanticscholar   +1 more source

Introgression of crop alleles into wild or weedy populations

, 2013
The evolutionary significance of introgression has been discussed for decades. Questions about potential impacts of transgene flow into wild and weedy populations brought renewed attention to the introgression of crop alleles into those populations.
N. Ellstrand, P. Meirmans, J. Rong, D. Bartsch, Atiyo Ghosh, T. J. Jong, P. Haccou, B. Lu, A. Snow, C. Stewart, Jared L. Strasburg, P. H. Tienderen, K. Vrieling, D. Hooftman   +13 more
semanticscholar   +1 more source

Time of the S Allele Action

Nature, 1958
THE genetic systems of self-incompatibility among the homomorphic flowering plants have been broadly subdivided into two groups1: (1) ‘gametophytic systems’ in which the pollen reaction is determined by the S allele contained in the pollen (Leguminosae, Scrophulariaceae, Solanaceae, Gramineae) and (2) ‘sporophytic systems’ in which the pollen reaction ...
openaire   +3 more sources