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Estimating Allele Age

Annual Review of Genomics and Human Genetics, 2000
The age of an allele can be estimated both from genetic variation among different copies (intra-allelic variation) and from its frequency. Estimates based on intra-allelic variation follow from the exponential decay of linkage disequilibrium because of recombination and mutation.
Montgomery Slatkin, Bruce Rannala
openaire   +3 more sources

On the Genealogy of a Rare Allele

Theoretical Population Biology, 1997
The gene genealogy is derived for a rare allele that is descended from a mutant ancestor that arose at a fixed time in the past. Following Thompson (1976, Amer. J. Human Genet. 28, 442-452), the fractional linear branching process is used as a model of the demography of a rare allele.
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Segregation of alleles

1981
You probably already know about segregation of alleles and assortment of non-alleles (the topics of this chapter and the next) from an undergraduate course in general genetics. I assume that you also know about the behaviour of chromosomes during mitosis, meiosis and fertilisation and that you know genes are carried on chromosomes.
openaire   +2 more sources

Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

Nature, 1996
M. Samson   +21 more
semanticscholar   +1 more source

The sampling theory of selectively neutral alleles.

Theoretical Population Biology, 1972
W. Ewens
semanticscholar   +1 more source

Prediction of bone density from vitamin D receptor alleles

Nature, 1994
N. Morrison   +7 more
semanticscholar   +1 more source

Widespread Parallel Evolution in Sticklebacks by Repeated Fixation of Ectodysplasin Alleles

Science, 2005
Pamela F. Colosimo   +9 more
semanticscholar   +1 more source

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

Nature, 1983
W. Cavenee   +9 more
semanticscholar   +1 more source

ALLELIC RESTRICTION

The Lancet, 1976
Michael Melnick, EdwardD. Shields
openaire   +3 more sources

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