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The use marker alleles for the introgression of linked quantitative alleles
Theoretical and Applied Genetics, 1977It is shown that when an exotic strain and a commercial strain differ genetically at a quantitative locus and at an adjoining marker locus, repeated backcrosses to the commercial strain, retaining only backcross progeny carrying the exotic marker allele, will allow the effective introgression of the linked quantitative allele from the exotic to the ...
J. Plotkin-Hazan, M. Soller
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2014
Methods used to understand the function of a gene/protein are one of the hallmarks of modern molecular genetics. The ability to genetically manipulate bacteria has become a fundamental tool in studying these organisms and while basic cloning has become a routine task in molecular biology laboratories, generating directed mutations can be a daunting ...
McKenzie K, Lehman+2 more
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Methods used to understand the function of a gene/protein are one of the hallmarks of modern molecular genetics. The ability to genetically manipulate bacteria has become a fundamental tool in studying these organisms and while basic cloning has become a routine task in molecular biology laboratories, generating directed mutations can be a daunting ...
McKenzie K, Lehman+2 more
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Frequency of Gc Alleles and a Variant Gc Allele in Iceland
Human Heredity, 1980The gene frequency for Gc1 and Gc2 in an Icelandic population was found to be 0.71 and 0.29, respectively. An electrophoretic variant similar to Gc Norway was detected in 5 individuals of the same family. A pedigree of 14 family members, including two spouses, is presented.
Gudmundur Thordarson+3 more
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Simultaneous estimation of null alleles and inbreeding coefficients.
Journal of Heredity, 2009Although microsatellites are a very efficient tool for many population genetics applications, they may occasionally produce "null" alleles, which, when present in high proportion, may affect estimates of key parameters such as inbreeding and relatedness ...
I. Chybicki, J. Burczyk
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Theoretical Population Biology, 2001
A subpopulation D of rare alleles is considered. The subpopulation is part of a large population that evolves according to a Moran model with selection and growth. Conditional on the current frequency, q, of the rare allele, an approximation to the distribution of the genealogy of D is derived.
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A subpopulation D of rare alleles is considered. The subpopulation is part of a large population that evolves according to a Moran model with selection and growth. Conditional on the current frequency, q, of the rare allele, an approximation to the distribution of the genealogy of D is derived.
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Introgression of crop alleles into wild or weedy populations
, 2013The evolutionary significance of introgression has been discussed for decades. Questions about potential impacts of transgene flow into wild and weedy populations brought renewed attention to the introgression of crop alleles into those populations.
N. Ellstrand+13 more
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Nature, 1958
THE genetic systems of self-incompatibility among the homomorphic flowering plants have been broadly subdivided into two groups1: (1) ‘gametophytic systems’ in which the pollen reaction is determined by the S allele contained in the pollen (Leguminosae, Scrophulariaceae, Solanaceae, Gramineae) and (2) ‘sporophytic systems’ in which the pollen reaction ...
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THE genetic systems of self-incompatibility among the homomorphic flowering plants have been broadly subdivided into two groups1: (1) ‘gametophytic systems’ in which the pollen reaction is determined by the S allele contained in the pollen (Leguminosae, Scrophulariaceae, Solanaceae, Gramineae) and (2) ‘sporophytic systems’ in which the pollen reaction ...
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The distribution of rare alleles
Journal of Mathematical Biology, 1995Population geneticists have long been interested in the behavior of rare variants. The definition of a rare variant has been the subject of some debate, centered mainly on whether alleles with small relative frequency should be considered rare, or whether alleles with small numbers should be.
Simon Tavaré, Paul Joyce
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On the Genealogy of a Rare Allele
Theoretical Population Biology, 1997The gene genealogy is derived for a rare allele that is descended from a mutant ancestor that arose at a fixed time in the past. Following Thompson (1976, Amer. J. Human Genet. 28, 442-452), the fractional linear branching process is used as a model of the demography of a rare allele.
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