Characterising the allergen landscape in paediatric allergic rhinitis and/or asthma. [PDF]
Chen Y +6 more
europepmc +1 more source
This study presents a post hoc analysis of longitudinal changes in peanut component‐specific IgE and IgG4 in children aged 1–4 years undergoing peanut SLIT, aiming to uncover immune mechanisms and potential biomarkers of remission. Peanut SLIT reduced IgE and increased IgG4 responses to Ara h 1, Ara h 2, Ara h 3, and Ara h 6.
Neel Singh +9 more
wiley +1 more source
Clinical manifestations and cross-reactions between cockroaches and termites and identification of termites' major allergens. [PDF]
Lee MF, Wu CS, Lin TM, Li HF, Chen YH.
europepmc +1 more source
Club Cells in Nasal Epithelial Repair: Insights From an IL‐13‐Induced Inflammatory Model
Four inflammatory endotypes of CRSwNP, defined by eosinophil and neutrophil infiltration, show distinct patterns of basal, club, ciliated, and goblet cell expression in nasal epithelium. Using an ALI‐HNECs model, we demonstrate that IL‐13 impairs mucociliary function by promoting club‐to‐goblet cell differentiation while inhibiting club‐to‐ciliated ...
Zhi‐Qun Huang +13 more
wiley +1 more source
Cockroach sensitization and its hidden links to mite and food allergens. [PDF]
Sobczak M +3 more
europepmc +1 more source
Conventional tests, such as specific IgE (sIgE) or intradermal testing (IDT), are usually sufficient. Combining both tests increases sensitivity, while additional tests, like the basophil activation test (BAT), provide no further benefit for the majority of patients.
Lisa Arzt‐Gradwohl +8 more
wiley +1 more source
Comparison of dominant foodborne and inhalant allergies developing in the first 5 years of life. [PDF]
Xu Q +7 more
europepmc +1 more source
Nail Dystrophy Treated With Marigold Therapy in a Patient With Epidermolysis Bullosa Simplex
Australasian Journal of Dermatology, EarlyView.
Aalia Syed +2 more
wiley +1 more source
Oral Immunotherapy Induces Shift in lncRNA Expression Modulating Allergen‐Specific Immune Responses
We used PBMC transcriptome from 50 hen's egg‐allergic patients to study the role of lncRNA in OIT. Positive correlation was found between 17 lncRNAs and the IL‐4/IL‐13 pathway in vivo, and the expression of the selected lncRNA aligned with CXCL8 upon PBMC egg‐restimulation.
Olivia Liong +5 more
wiley +1 more source
Dual dimensions of sensitization: age-stratified and disease-associated sIgE profiles in pediatric eczema and urticaria. [PDF]
Yang L +8 more
europepmc +1 more source

