Results 91 to 100 of about 415,351 (305)

Peripheral blood Th9 cells and eosinophil apoptosis in asthma patients

Medicina, 2015
Background and objective: Th9 cells producing interleukin (IL) 9 are novel subset of CD4+ T helper cells, which might contribute to airway inflammation in asthma. Moreover, the effect of IL-9 on eosinophils is still not fully understood. Study aim was to
Deimantė Hoppenot, Kęstutis Malakauskas, Simona Lavinskienė, Ieva Bajoriūnienė, Virginija Kalinauskaitė, Raimundas Sakalauskas   +5 more
doaj   +1 more source

Maternal intake of fatty acids during pregnancy and allergies in the offspring [PDF]

, 2011
Fatty acids (FA) are known to have a number of immunological effects and, accordingly, may play a role in the development of allergic diseases. We investigated the effect of maternal intake of FA during pregnancy on the risk of allergic rhinitis, wheeze ...
Veijola, Riitta, Maijaliisa Erkkola, Jorma Ilonen, Suvi Ahonen, Erkkola, Maijaliisa, Riitta Veijola, Suvi M. Virtanen, Mikael Knip, Knip, Mikael, Virtanen, Suvi M., Kronberg-Kippila, Carina, Simell, Olli, Mirka Lumia, Minna Kaila, Nwaru, Bright I., Kaila, Minna, Nwaru, Bright I, Olli Simell, Bright I. Nwaru, Lumia, Mirka, Virtanen, Suvi M, Ilonen, Jorma, Carina Kronberg-Kippilä, Ahonen, Suvi   +23 more
core   +1 more source

Tezepelumab in Chinese Patients With Severe Chronic Rhinosinusitis With Nasal Polyps: A Prespecified Subgroup Analysis of the Phase 3 WAYPOINT Trial

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) in Chinese patients often exhibits a mixed Type 1/2/3 inflammatory phenotype (63%), potentially impacting the efficacy of biologics targeting Type 2 inflammation. This prespecified subgroup analysis of WAYPOINT (NCT04851964) evaluated the efficacy and safety of tezepelumab in Chinese
Li Hu, Houyong Li, Xicai Sun, Quan Liu, Yu Xu, Jiangang Fan, Andrew Foster, Claudia Chen, Yun Chon, Dehui Wang   +9 more
wiley   +1 more source

Allergic asthma and rhinitis comorbidity

Vojnosanitetski pregled, 2015
nema
Zvezdin Biljana, Hromiš Sanja, Kolarov Violeta, Milutinov Senka, Zarić Bojan, Jovančević Ljiljana, Ilić Miroslav   +6 more
openaire   +3 more sources

Inflammatory Signatures Beyond Th1/Th2 Endotypes Provide Insights Into Postoperative Recurrence in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) represents a spectrum of inflammatory endotypes, driven by distinct T helper (Th) immune responses. The high rate of recurrent disease despite appropriate medical and surgical interventions highlights the need for improved characterization beyond the traditional type 2 and non‐type 2 phenotypes to better
Liyona Kampel, Narin N. Carmel, Shaun Edalati, Hen Chaushu, Forsan Jahshan, Yaniv Hadi, Timur Pestrikov, Leonor Leider Trejo, Nidal Muhanna, Avraham Abergel   +9 more
wiley   +1 more source

Host‐Specific Interactions Between Staphylococcus aureus and Pseudomonas aeruginosa Impair Epithelial Repair in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is frequently associated with polymicrobial biofilms involving Staphylococcus aureus and Pseudomonas aeruginosa. Interactions between these organisms are thought to influence disease severity, but the epithelial effects of exoproteins derived from patient‐matched cocultures remain poorly defined ...
Xiaohan Sun, Mahnaz Ramezanpour, George Bouras, Emma Barry, Alkis J. Psaltis, Peter‐John Wormald, Sarah Vreugde   +6 more
wiley   +1 more source

microRNA profiling and target identification in a mouse model for allergic asthma [PDF]

, 2012
Allergic asthma has a high prevalence and is characterized by airway inflammation, tissue remodeling and a decline in respiratory function. Although the pathogenesis is well known, the underlying mechanisms are still poorly understood.
Schulz, N., Schulz, Nikola
core   +1 more source

Exposure to indoor microbial agents, allergens and pets, and their relation to asthma and allergy prevalence in farmers' children and their peers from rural areas : Diploma thesis [PDF]

, 2004
Background In ‘westernised’ countries, the prevalence of childhood asthma and allergy have risen throughout the last three decades. Changes in lifestyle and environmental factors like an increase in exposure to air pollutants, environmental tobacco smoke,
Waser, Marco
core   +1 more source

Clinical Longitudinal Evaluation After Regimen Stop (CLEAR) of Dupilumab in Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Long‐term management strategies for severe chronic rhinosinusitis with nasal polyps (CRSwNP) increasingly include biologic therapy targeting Type 2 inflammation. However, data on outcomes after complete discontinuation of dupilumab following sustained disease control are scarce.
Patrick Huber, Manuel Lasch, Veronika Volgger, Clemens Stihl, Philipp Teupe, Fabienne Oettgen, Sophia Gantner, Moritz Gröger   +7 more
wiley   +1 more source

Differences between rural and urban primary care practices in asthma and allergic rhinitis control: the Greek experience

Rural and Remote Health
Introduction: Limited data exist on allergic rhinitis and asthma control in rural primary care. Therefore, the aim of our study was to assess asthma and comorbid allergic rhinitis control in patients attending primary care in both urban and rural ...
Eirini Lambraki, Izolde Bouloukaki, Katerina Margetaki, Nikolaos Tzanakis, Alexandros Karatzanis, Ioanna Tsiligianni   +5 more
doaj   +1 more source