Results 201 to 210 of about 415,351 (305)

Deciphering the Inflammatory Network in Pediatric Recurrent Tonsillitis: The Role of TRAF6, IRAK1, and miR‐146a‐5p

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To investigate the role of TNF receptor‐associated factor 6 (TRAF6), interleukin 1 receptor‐associated kinase 1 (IRAK1), and miR‐146a‐5p expression levels in the pathogenesis of recurrent tonsillitis. Study Design Case‐control study. Setting The study was conducted at the Department of Otorhinolaryngology, Muğla Training and Research
Ömer Faruk Güzel, Çilem Özdemir, Tuba Edgünlü, Ozan Gökdoğan   +3 more
wiley   +1 more source

Targeting the Epithelial Alarmin Axis with Biomedical Nanoparticles: A New Frontier in Allergic Asthma Therapy. [PDF]

Int J Nanomedicine
Yang Y.
europepmc   +1 more source

Efficacy of Exhalation Delivery System With Fluticasone in Chronic Rhinosinusitis With Versus Without Polyps

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate whether treatment responses to the exhalation delivery system with fluticasone (EDS‐FLU; XHANCE®) differ between patients with CRS with nasal polyps (CRSwNP) and patients without nasal polyps (CRSsNP). Study Design Post hoc analysis of the ReOpen clinical trials conducted between November 2018 and November 2021 for a 24 ...
Rodney J. Schlosser, Nithin D. Adappa, Rakesh K. Chandra, Greg E. Davis, Mahboobeh Mahdavinia, John Messina, Zara M. Patel, Anju T. Peters, Raj Sindwani, Zachary M. Soler, Andrew A. White, Sarah K. Wise, James N. Palmer   +12 more
wiley   +1 more source

<i>Leonurus japonicus</i> Houtt. extract containing isoquercitrin reduces airway inflammation in mice with allergic asthma. [PDF]

Front Pharmacol
Guimarães CC, Borges MC, Fabro AT, Cardoso PH, Acunha T, Faccioli LH, Pereira SIV, Contini SHT, França SC, Carmona F, Pereira AMS.   +10 more
europepmc   +1 more source

Efficacy of Endoscopic Sinus Surgery for Allergic Fungal Rhinosinusitis: A Systematic Review With Meta‐analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Endoscopic sinus surgery (ESS) plays a central role in the management of allergic fungal rhinosinusitis (AFRS); however, outcomes vary across studies. The goal of this study is to systematically review and synthesize evidence on the outcomes of ESS in patients with AFRS.
Amani Kais, Jad Kfouri, Ahmad R. Sedaghat, Charles Alex Riley, Chadi A. Makary   +4 more
wiley   +1 more source

Regulatory T-cell-biased IL-2 mutein inhibits development of allergen-specific T_H2 cells and allergic asthma. [PDF]

J Allergy Clin Immunol
Selle A, Yero A, Moon JJ, Campbell DJ, Luster AD.   +4 more
europepmc   +1 more source

Glucocorticoids Impair the Airway Epithelial Barrier via Autophagy‐Associated Apoptosis in Asthma: A Preliminary Study Both In Vitro and In Vivo

Pediatric Discovery, EarlyView.
Mechanism underlying the negative effects of glucocorticoids on the airway epithelial barrier. Glucocorticoids upregulate autophagy factors and downregulate anti‐autophagy factors. Enhanced autophagy promotes excessive apoptosis and epithelial detachment, impairing airway barrier function.
Hao You, Wenjing Zou, Tangqiaochu Gan, Yu Zhao, Jie Hu, Wen Tan, Ting Wang, Luo Ren, Zhengxiu Luo, Zhou Fu, Chao Niu   +10 more
wiley   +1 more source

Lysophosphatidic Acid Receptor 5 (LPA₅) Antagonist AS2717638 Attenuates Allergic Asthma by Reducing Mast Cell Degranulation and Th2 Inflammation in Mice. [PDF]

Int J Mol Sci
Jeong SW, Im DS.
europepmc   +1 more source

Respiratory profile of pediatric patients undergoing hematopoietic stem cell transplantation studied by oscillometry – A TRANSPIRE cohort

Pediatric Investigation, EarlyView.
These are results from a multi‐center collaboration between four large pediatric institutions, investigating baseline respiratory system function in a cohort of children undergoing hematopoietic stem cell transplantation. This manuscript proposes respiratory oscillometry as a novel way to prospectively follow lung function in these children.
Maureen B. Parenti, Julian Allen, Lisa R. Young, Heather Boas, Jason Freedman, Christopher Towe, Jane Koo, Kasiani Myers, Jason C. Woods, Adam Lane, Jonathan Gaffin, Wai Wong, Leslie Lehmann, Fernando Urrego, Gabriel Salinas Cisneros, Matthew F. Abts, K. Scott Baker, Manuel Silva‐Carmona, Erin Doherty, Paul D. Robinson, Margaret MacMillan, Stella M. Davies, Samuel B. Goldfarb   +22 more
wiley   +1 more source

Blood Eosinophil Subtype-Specific Protein Gene Expression and Eosinophil-Derived Serum Mediators in Allergic Asthma Patients After Bronchial Challenge with <i>Dermatophagoides pteronyssinus</i>. [PDF]

Cells
Rimkunas A, Januskevicius A, Vasyle E, Palacionyte J, Miliauskas S, Malakauskas K.   +5 more
europepmc   +1 more source