Results 101 to 110 of about 29,640 (301)

Safety, tolerability, pharmacokinetics and pharmacodynamics of the spleen tyrosine kinase inhibitor BI 894416 in healthy volunteers and patients with asthma

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche   +8 more
wiley   +1 more source

Allergic conjunctivitis

open access: yes, 2021
Conjunctiva is a thin layer that covers the eye and the inside of the eyelids and is almost ten times more sensitive to allergens than the skin, because it is constantly exposed to a wide variety of microorganisms and allergens. But the eye as an organ is able to protect itself without changing its own structure and function thanks to the anatomical ...
Emini, Sheribane, Gazepov, Strahil
openaire   +1 more source

Rhinitis in general practice [PDF]

open access: yes, 2007
A 3 year old boy presented with a 3 week history of nasal obstruction, clear rhinorrhea, difficulty with feeding and a productive cough. Child was afebrile, had occasional watery itchy eyes and mother claimed that at night he tended to wake up a couple ...
drkvassallo@yahoo.co.uk   +1 more
core  

Allergic diseases in the elderly: biological characteristics and main immunological and non-immunological mechanisms [PDF]

open access: yes, 2017
Life expectancy and the number of elderly people are progressively increasing around the world. Together with other pathologies, allergic diseases also show an increasing incidence in geriatric age.
Bonini M   +12 more
core   +1 more source

Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study

open access: yesClinical &Experimental Allergy, Volume 55, Issue 3, Page 226-238, March 2025.
In a study assessing mobile health data, (i) adherence to rhinitis medication was highest for oral antihistamines and lowest for azelastine‐fluticasone, (ii) in weeks of partial adherence, azelastine‐fluticasone was associated with lower levels of reported rhinitis symptoms than other medication classes.
Bernardo Sousa‐Pinto   +121 more
wiley   +1 more source

Sensitization patterns and minimum screening panels for aeroallergens in self-reported allergic rhinitis in China [PDF]

open access: yes, 2017
Optimization of skin prick test (SPT) panels, especially in view of significant differences in sensitizations patterns within different geographical areas, is an unmet need within China.
Bachert, Claus   +9 more
core   +3 more sources

Patient‐Derived IgG Epitope Mapping of Bet v 1 Reveals Hypoallergenic Peptide Candidates for Safe and Next‐Generation Allergen Immunotherapy

open access: yesClinical &Experimental Allergy, EarlyView.
Mapping IgG epitopes of the major birch allergen Bet v 1 identified patient‐derived, hypoallergenic peptides that did not trigger degranulation. These findings support a novel, safer approach for peptide‐based allergen immunotherapy that leverages naturally induced IgG specificities from allergic individuals. ABSTRACT Background Allergen immunotherapy (
Lara Šošić   +10 more
wiley   +1 more source

Maternal sleep disorders during pregnancy and subsequent risk of allergic diseases in Japanese children: the TMM BirThree Cohort Study [PDF]

open access: yesClinical and Experimental Pediatrics
Background Associations have been suggested between prenatal exposure and allergic diseases in children as well as between respiratory allergies and maternal sleep disorders during pregnancy.
Ami Uematsu   +7 more
doaj   +1 more source

GAMBARAN JUMLAH EOSINOFIL MUKOSA KONJUNGTIVA MATA DAN DERAJAT KEPARAHAN KLINIS PENYAKIT KONJUNGTIVITIS ALERGI [PDF]

open access: yes, 2016
Samuel Fiergeon Picardi, G0012204, 2015. Gambaran jumlah eosinofil mukosa konjungtiva mata dan derajat keparahan klinis penyakit konjungtivitis alergi. Skripsi. Fakultas Kedokteran Universitas Sebelas Maret, Surakarta. Latar Belakang: Eosinofil adalah
Picardi, Samuel Fiergeon
core  

Femtosecond Laser Created Corneal Allogenic Intrastromal Ring Segments for Keratoconus

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To evaluate the clinical outcomes of femtosecond laser‐created corneal allogenic intrastromal ring segments (femto‐CAIRS) in keratoconic eyes using a newly described nomogram. Methods This retrospective case series recruited 85 eyes from 75 patients.
David J. Gunn   +2 more
wiley   +1 more source

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