Results 91 to 100 of about 1,326 (169)

Cadherin‐26 Facilitates Transepithelial Migration of Eosinophils in Eosinophilic Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) is characterized by persistent sinonasal inflammation and marked eosinophilic infiltration. Although the relationship between eosinophils and NP formation has been extensively studied, the mechanisms governing eosinophil transepithelial migration into the nasal mucosa ...
Yeong‐In Jo, Jee Won Moon, Joo‐Hoo Park, Hwa Eun Yang, Subin Cho, Hyeongguk Son, Hyun‐Woo Yang, Il‐Ho Park   +7 more
wiley   +1 more source

New approaches to treating chronic obstructive pulmonary disease with Colla corii asini

Animal Models and Experimental Medicine, EarlyView.
Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang, Siman Sun, Xiaoyu Fan, Jiuming He, Qing Li, Hongtao Jin   +5 more
wiley   +1 more source

Molecular dynamics of the host response to Streptococcus pneumoniae pneumonia in baboons

Animal Models and Experimental Medicine, EarlyView.
Using an established, clinically relevant nonhuman primate model of S. pneumoniae pneumonia, this study aims to identify novel potential molecular diagnostic and therapeutic targets using peripheral blood bulk transcriptomic, unbiased proteomic, and cytokine measurements. The constructed models were highly accurate in classifying bacterial pneumonia in
Bryan D. Kraft, Ashlee M. Valente, Ephraim L. Tsalik, Micah T. McClain, Marshall Nichols, Thomas W. Burke, Ricardo Henao, Erik J. Soderblom, J. Will Thompson, M. Arthur Moseley, Lori L. Hudson, Timothy Veldman, Olga M. Better, Mert Aydin, Anna Mazur, Karen E. Welty‐Wolf, Claude A. Piantadosi, Geoffrey S. Ginsburg, Christopher W. Woods   +18 more
wiley   +1 more source

0D Fluorescent Nanomaterials: Preparation, Properties, and its Antibacterial Applications

Advanced NanoBiomed Research, EarlyView.
This article reviews the synthesis methods and typical properties of representative 0D fluorescent nanomaterials such as carbon dots, quantum dots, and metal nanoclusters, while also exploring their antibacterial applications in various fields including medical and health care, food, agriculture, and industry.
Tianyi Lu, Jiangxue Dong, Yanlei Li, Jingjing Wang, Ming Su, Yajie Fan, Shigang Shen, Zhongfeng Gao   +7 more
wiley   +1 more source

Multifunctional Hydrogel‐Based wound Dressings for Scar‐Free Healing: Design Principles, Therapeutic Mechanisms, and Clinical Translation Challenges

Advanced NanoBiomed Research, EarlyView.
This review integrates scar biology with hydrogel‐based therapeutic strategies, offering a phase‐specific framework to correlate hydrogel functions with scar‐influencing events. It highlights innovations such as stimuli‐responsive hydrogels, nanocomposite systems, and 3D‐printed scaffolds, while addressing clinical translation challenges like ...
Haonan Chai, Zhenxing Wang, Jingyi Ju, Jiaming Sun   +3 more
wiley   +1 more source

Mucosal‐Associated Invariant T Cells in Rheumatic Diseases

Arthritis &Rheumatology, EarlyView.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek, Virginie Gonzalez, Lucie Beaudoin, Noémie Sénot, Corinne Miceli‐Richard, Yannick Allanore, Agnès Lehuen, Jerôme Avouac   +7 more
wiley   +1 more source

Efficacy and Safety of ABBV‐154 for the Treatment of Active Rheumatoid Arthritis: A Phase 2b, Randomized, Placebo‐Controlled Trial

Arthritis &Rheumatology, EarlyView.
Objective Despite the availability of biologic and targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) to treat rheumatoid arthritis (RA), many patients do not experience optimized disease control. Glucocorticoids are effective but have safety risks.
Frank Buttgereit, Atul Singhal, Alan Kivitz, Edit Drescher, Yoshinori Taniguchi, Rosalía Martínez Pérez, Jaclyn Anderson, Ronilda D'Cunha, Weihan Zhao, Nicholas DeVogel, Julie Parmentier, Romy Christmann, Dilek Arikan, Howard Amital   +13 more
wiley   +1 more source

Rehabilitation Interventions Delivered via Telehealth to Support Self‐Management of Rheumatic and Musculoskeletal Disease: A Scoping Review

Arthritis &Rheumatology, EarlyView.
Objective To identify and summarize existing telerehabilitation interventions for people living with rheumatic and musculoskeletal diseases (RMDs), including the rehabilitation components, the technology used, the type of health care professional (HCP) interaction, and how the effectiveness is evaluated.
Thomas A. Ingram, Rosemarie Barnett, Nuzhat Shakaib, Simon Jones, Raj Sengupta, Peter C. Rouse   +5 more
wiley   +1 more source

Linking Skin and Joint Inflammation in Psoriatic Arthritis through Shared CD8+ T Cell Clones

Arthritis &Rheumatology, EarlyView.
Objective Psoriatic arthritis (PsA) is an HLA class I–associated inflammatory arthritis that develops in up to 30% of people with psoriasis. We tested the hypothesis that skin and joint inflammation in PsA is linked in terms of CD8+ T cell phenotype and clonality.
Lucy E. Durham, Frances Humby, Nora Ng, Roman Laddach, Elizabeth H. Gray, Sarah E. Ryan, Kathryn J. A. Steel, Rosie Ross, Giovanni A. M. Povoleri, Rosamond Nuamah, Kathy Fung, Athul Menon Kallayil, Pawan Dhami, Bruce W. Kirkham, Leonie S. Taams   +14 more
wiley   +1 more source

Allergic contact dermatitis to lettuce [PDF]

Anais Brasileiros de Dermatologia
Mariany Lima Rezende, Ana Luiza Castro Fernandes Villarinho, Maria das Gracas Mota Melo, Clarissa Vita Campos   +3 more
doaj   +1 more source