Results 101 to 110 of about 211,122 (354)

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

open access: yesAdvanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang   +16 more
wiley   +1 more source

Mishaps during composite restoration: Acute allergic angioedema and contact dermatitis

open access: hybrid, 2023
Vanshish Sankhyan   +3 more
openalex   +1 more source

Health Hazard Manual For Cutting Oils, Coolants, and Metalworking Fluids [PDF]

open access: yes, 1991
[Excerpt] The metalworker can be exposed to cutting oils during application by two basic routes of entry: skin contact and inhalation. The higher risk jobs tend to be those with high cutting speeds, heavy oil flow, and continuous contact, which may ...
Brown, Nellie J
core   +1 more source

Contact urticaria to giraffe hair [PDF]

open access: yes, 2005
Background: Immediate-type hypersensitivity to animal proteins is a common problem in people occupationally exposed to animals. Methods: A 19-year-old female working as a voluntary zookeeper in her off-time suffered from hives on her forearms following ...
Herzinger, T.   +3 more
core   +1 more source

Notch2 Directs aTreg Cell Fate toward Immunoregulation or Inflammatory Pyroptosis

open access: yesAdvanced Science, EarlyView.
Schematic illustration showing that the Notch2 intracellular domain (NICD2) facilitates pyroptosis resistance in activated Tregs through the RREB1/Foxo1 signaling pathway. In addition, Notch2‐mediated pyroptosis resistance in activated Tregs promotes immunoregulatory capacity, thereby attenuating Th2‐driven inflammatory responses in allergic rhinitis ...
Yue‐Long Qiao   +10 more
wiley   +1 more source

Early probiotic supplementation for the prevention of atopic disease in newborns-probiotics and the hygiene hypothesis-. [PDF]

open access: yes, 2011
Environmental factors during early infancy could theoretically affect immune system development and subsequent risk of allergic disease. One potentially helpful exposure is early infant supplementation with specific probiotic strains.
Cabana, Michael D
core   +3 more sources

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

open access: yesAdvanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta   +14 more
wiley   +1 more source

Allergic contact dermatitis of both eyes caused by alcaftadine 0.25%: a case report

open access: yesBMC Ophthalmology, 2019
Background To report the first case of allergic contact dermatitis (ACD) associated with alcaftadine 0.25% ophthalmic solution. Case presentation The patient was a 51-year-old woman with no previous history of side effects to ophthalmic antihistamine ...
Jae Hyuk Kim   +2 more
doaj   +1 more source

Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides

open access: yesAdvanced Science, EarlyView.
This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das   +13 more
wiley   +1 more source

Topical Sunscreens: A Narrative Review for Contact Sensitivity, Potential Allergens, Clinical Evaluation, and Management for their Optimal Use in Clinical Practice

open access: yesIndian Dermatology Online Journal
Topical sunscreens decrease the quantity of ultraviolet (UV) light from the sun reaching the skin by either blocking or scattering it and help protect the skin from dyspigmentation, photoaging, DNA damage, and photocarcinogenesis, especially in ...
Vikram K. Mahajan   +5 more
doaj   +1 more source

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