Results 121 to 130 of about 60,534 (304)

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Contact sensitisers activate keratinocytes and induce cytotoxicity via Transient Receptor Potential Ankyrin 1 in allergic contact dermatitis

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Allergic contact dermatitis (ACD) is a frequent inflammatory skin disease with limited therapeutic options. While neuronal Transient Receptor Potential Ankyrin 1 (TRPA1) has been implicated in ACD, the role of keratinocyte TRPA1 remains unclear.
Areej Jaber, Szabina Horváth, Balázs Zoltán Zsidó, Viktória Kormos, János Konkoly, Csaba Hetényi, Erika Pintér, Ágnes Kemény, Rolland Gyulai   +8 more
wiley   +1 more source

Early Detection of Lower Adherence to Long‐Term e‐Diary Recording: A Checkpoint to Target Early Educational Intervention in Seasonal Allergic Rhinitis?

Clinical &Experimental Allergy, EarlyView.
Adherence to e‐Diary reporting was investigated in a blended care setting among pollen allergic patients with heterogeneous cultural backgrounds. A stable ‘higher’ and a more variable ‘lower’ adherence cluster were identified. Early identification of lower adherence is possible and might inform early interventions to improve patient adherence. ABSTRACT
S. Dramburg, C. J. Hernandez Toro, U. Grittner, S. Tripodi, S. Arasi, A. Acar Şahin, X. Aggelidis, A. Barbalace, A. Bourgoin, B. Bregu, M. A. Brighetti, E. Caeiro, S. Caglayan Sozmen, L. Caminiti, D. Charpin, M. Couto, L. Delgado, A. Di Rienzo Businco, C. Dimier, M. V. Dimou, J. A. Fonseca, O. Goksel, D. Hernandez, T. M. Hoffmann, D. T. Jang, F. Kalpaklioglu, B. Lame, R. Llusar, M. Makris, A. Mazon, E. Mesonjesi, A. Nieto, A. Öztürk, L. Pahus, G. Pajno, I. Panasiti, N. G. Papadopoulos, E. Pellegrini, S. Pelosi, A. M. Pereira, M. Pereira, N. M. Pinar, E. Potapova, A. Priftanji, F. Psarros, C. Sackesen, I. Sfika, J. Suarez, M. Thibaudon, A. Travaglini, U. Uguz, V. Verdier, V. Villella, P. Xepapadaki, D. Yazici, P. M. Matricardi   +55 more
wiley   +1 more source

How safe are herbal products? [PDF]

, 2000
In the search for cures for his ailments, man discovered many healing and toxic properties of plants. Some were found to cure certain diseases while others were found to exert dramatic effects on the body.
Forte, John Stephen
core  

A case of tinea incognito mimicking subcorneal pustular dermatosis [PDF]

, 2020
An 89-year-old woman presented with plaque-like lesions, accompanied with pustules and desquamation on the back and front of the trunk for approximately one year. Long term use of potent topical corticosteroids was ineffective.
Aktaş, Akın, Demirseren, D Deniz, Güney, Cansu Altınöz, Kalkan, Göknur   +3 more
core  

Malassezia‐Induced Type 2 Immunity in Head Neck Shoulder Type Atopic Dermatitis

Allergy, EarlyView.
I. Suhrkamp, T. Heidland, C. Saft, A. K. Kamps, S. Edenhart, O. Kniemeyer, W. Francuzik, S. Weidinger, P. Bacher, C. Bang, G. Heine   +10 more
wiley   +1 more source

Clinical Factors Associated With Current Relevance in Allergic Contact Dermatitis: Development of Predictive Models Based on Data From the Spanish Contact Dermatitis Register (REIDAC)

Contact Dermatitis, EarlyView.
This study has shown a moderate performance of the regression model to predict current relevance (AUC = 0.679), although modelling performance has been better for specific allergens (e.g., nickel with an AUC = 0.770). Furthermore, it has identified key predictors, including female gender, specific involved sites (hands, neck, head, legs, feet), and ...
David Pesqué, Francisco Javier Ortiz de Frutos, Francisco Navarro‐Triviño, Tatiana Sanz‐Sánchez, Violeta Zaragoza‐Ninet, Susana Córdoba‐Guijarro, Javier Miquel‐Miquel, Juan Francisco Silvestre‐Salvador, Ricardo González‐Pérez, Inmaculada Ruiz‐González, Pedro Mercader‐García, Esther Serra‐Baldrich, José Manuel Carrascosa‐Carrillo, Fátima Tous‐Romero, Mercedes Rodríguez‐Serna, María Elena Gatica‐Ortega, Carmen Paredes‐Suárez, María Antonia Pastor‐Nieto, Pablo Chicharro, Marta Andreu, Araceli Sánchez‐Gilo, José Juan Pereyra‐Rodríguez, Gemma Melé‐Ninot, Paloma Sánchez‐Pedreño Guillén, Enrique Gómez de la Fuente, Marta Elosua‐González, Fernando Gallardo, Ramon M. Pujol, Ignacio García‐Doval, Leopoldo Borrego, Miguel Ángel Descalzo, Ana M. Giménez‐Arnau   +31 more
wiley   +1 more source

Real‐Life Workup of Chronic Hand Eczema Using a Dedicated Case Report Form: A SIDAPA Multicentre Study

Contact Dermatitis, EarlyView.
From January 2024 to May 2025, 207 patients (68.6% females) affected by CHE were enrolled to be clinically and etiologically investigated using a case report form specifically developed. The accurate workup led to clinical and etiological classification of CHE in about 80% of patients, allowing tailored treatment strategies. ABSTRACT Background Chronic
Rosella Gallo, Fabrizio Guarneri, Katharina Hansel, Luca Stingeni, Maddalena Napolitano, Cataldo Patruno, Monica Corazza, Alessandro Borghi, Ilaria Trave, Emanuela Martina, Maria Michela Lauriola, Rosanna Rita Satta, Caterina Foti, Paolo Romita, Roberta Giuffrida, Silvia Mariel Ferrucci, on behalf of SIDAPA CHE Study Group, Gabriele Biondi, Gabriele Casciola, Florenzia Marielli, Roberto Pinto, Ilaria Salvi   +21 more
wiley   +1 more source

Formaldehyde Emissions From 2‐Octyl Cyanoacrylate: Quantified Risk for Allergic Contact Dermatitis

Contact Dermatitis, EarlyView.
This study found that 2‐octyl cyanoacrylate skin adhesives release formaldehyde at levels up to 8.4× above EPA dermal thresholds and up to 2.41× above NIOSH airborne limits, producing exposures sufficient to provoke allergic and irritant contact dermatitis in patients.
Daniel S. Rouhani, Paul M. Villalobos, Steven Zeng, Reza Ghodsi, Kavana M. Sanjay, Simrin A. Singh, M. Mark Mofid   +6 more
wiley   +1 more source

Effect of Delgocitinib Cream on Health‐Related Quality of Life in Patients With Moderate to Severe Chronic Hand Eczema

Contact Dermatitis, EarlyView.
Patient‐reported outcomes are an important complement to physician‐assessed clinical outcome measures in Chronic Hand Eczema. In a pooled analysis of two randomised, controlled trials, twice‐daily treatment with delgocitinib cream 20 mg/g significantly improved the health‐related quality of life of patients with moderate to severe Chronic Hand Eczema ...
Andrea Bauer, Lyn Guenther, Richard Woolf, Eydna Didriksen Apol, Douglas Maslin, Nanna Nyholm, Henrik Thoning, Marie Louise Schuttelaar   +7 more
wiley   +1 more source