Results 121 to 130 of about 1,886,571 (257)

Allergic contact dermatitis due to 1,6-hexanediol diacrylate in ostomy patients [Elektronisk resurs]

Background: Many people live with ostomies after life-saving surgery. Ostomy patients often suffer from peristomal dermatitis. Allergic contact dermatitis (ACD) has been reported, mostly due to contact allergy (CA) to topical agents.
Svedman, Cecilia,, Dahlin, Jakob,, Mowitz, Martin,, Hamnerius, Nils,, Lund University., Siemund, Ingrid,   +5 more
core   +1 more source

Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres, Cristobalina Mayorga, Elizabeth J. Phillips, Adriana Ariza, Annick Barbaud, Patrizia Bonadonna, Mariana Castells, Gülfem Çelik, Knut Brockow, Lene H. Garvey, Inmaculada Doña, Jean‐Christoph Caubet, Francesca Mori, Jason Trubiano, Giorgia Marta, Antonino Romano, Ingrid Terreehorst, Asli Gelincik, Philip H. Li, Vito Sabato   +19 more
wiley   +1 more source

The External Exposome and Food Allergy: How Environmental Exposures Shape Disease Risk

Allergy, EarlyView.
ABSTRACT IgE‐mediated food allergy is a global health issue with rising prevalence that cannot be explained by genetic change alone, strongly suggesting that environmental exposures are a key driver. The external exposome encompasses several exposures that influence the developing immune system and modify food allergy risk.
Johanna M. Smeekens, Helen A. Brough, Kirsi M. Järvinen, Sophie Troyer, Michael D. Kulis, Timothy P. Moran   +5 more
wiley   +1 more source

Allergic contact dermatitis from dicyclohexylmethane-4,4 '-diisocyanate

, 2003
From August 1999 to April 2001, there was an outbreak of severe eczema at a factory manufacturing medical equipment. A glue, mainly based on the isocyanate dicyclohexylmethane-4,4'-diisocyanate (DMDI), was suspected as being the cause of the problem.
Hamnerius, N, Engfeldt, Malin,, Björkner, Bert,, Lund University., Zimerson, Erik,   +4 more
core   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, EarlyView.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

High release of hexavalent chromium into artificial sweat in a case of leather shoe–induced contact dermatitis

, 2019
Cases of allergic contact dermatitis due to chromium caused by chromium‐tanned leather articles such as shoes and gloves are well‐known.1, 2 In the European Union, hexavalent chromium in new leather articles on the market is restricted to 3 mg/kg since ...
Mihály Matura, Zheng Wei, Wei, Zheng,, Yolanda S. Hedberg, Matura, Mihaly,, Hedberg, Yolanda,   +5 more
core   +1 more source

Significantly Different Prevalences of Contact Allergy to Hydroperoxides of Linalool and Limonene When Patch Testing With Different Patch Test Chambers

Contact Dermatitis, EarlyView.
Finn Chamber AQUA (FCA) detects significantly higher contact allergy prevalences to linalool hydroperoxides (7.0% vs. 5.1% FC) and limonene hydroperoxides (7.8% vs. 3.0% FC, 3.8% IQ) than Finn Chamber (FC) or IQ Ultra (IQ) in 629 dermatitis patients; chamber choice is therefore crucial for diagnostics.
Henrik Luu, Thanisorn Sukakul, Magnus Bruze, Martin Mowitz, Cecilia Svedman   +4 more
wiley   +1 more source

Mapping of Former Strategies and Future Needs for Regulatory Prevention of Skin Sensitization: Cosmetic Products

Contact Dermatitis, EarlyView.
This study identified multiple areas for improvement in the regulatory risk assessment process. Conclusions based on predictive sensitization data should be made with caution, read‐across data from known sensitizers should be utilized, and epidemiological and patient threshold data should be prioritized in decision‐making.
Mathias Krogh Pedersen, Jakob Ferløv Baselius Schwensen, Jose Hernán Alfonso, Steen Mollerup, Gianluca Selvestrel, Christina Rudén, Martin F. Wilks, Jeanne Duus Johansen   +7 more
wiley   +1 more source

Allergic contact dermatitis in mice with interleukin-6 deficiency in dendritic cells

Медицинская иммунология
Contact dermatitis is a disease characterized by skin inflammation caused by external agents, most commonly, allergens. Patients with contact dermatitis have impaired skin barrier function, causing permeability of the epidermis layer.
E. A. Gorshkova, A. D. Medvedovskaya, E. O. Gubernatorova   +2 more
doaj   +1 more source