Results 61 to 70 of about 88,417 (375)

Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics

Advanced Healthcare Materials, EarlyView.
This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

The additive value of patch testing non‐commercial test substances and patients' own products in a clinic of occupational dermatology

Contact Dermatitis, Volume 88, Issue 1, Page 27-34, January 2023., 2023
At the Finnish institute of Occupational Health in 2015–2019, we would have missed 39 (18.9%) of our 206 cases of OACD if we had solely used commercial test substances. Abstract Background Commercial patch test substances do not cover all occupational contact allergens.
Kristiina Aalto‐Korte, Maria Pesonen
wiley   +1 more source

Apoptotic Vesicles Derived from Mesenchymal Stem Cells Ameliorate Hypersensitivity Responses via Inducing CD8+ T Cells Apoptosis with Calcium Overload and Mitochondrial Dysfunction

Advanced Science, EarlyView.
The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu, Peng Peng, Changze Wei, Fanhui Meng, Xiaoyao Huang, Peisheng Liu, Siyuan Fan, Xinyue Cai, Meiling Wu, Zilin Xuan, Qing Liu, Xinyu Qiu, Zhenlai Zhu, Hao Guo   +13 more
wiley   +1 more source

Nickel allergy is associated with a broad spectrum cytokine response

Contact Dermatitis, Volume 88, Issue 1, Page 10-17, January 2023., 2023
PBMC from nickel allergic patients and controls were stimulated with nickel under type 1, 2 and 17 skewing culture conditions; levels of 33 cyto‐ /chemokines were analysed and related to medical history of nickel contact dermatitis and nickel patch test result.
Niels P. J. De Graaf, Sanne Roffel, Susan Gibbs, Cees J. Kleverlaan, Marta Lopez Gonzalez, Thomas Rustemeyer, Albert J. Feilzer, Hetty J. Bontkes   +7 more
wiley   +1 more source

Sensitization properties of acetophenone azine, a new skin sensitizer identified in textile

Contact Dermatitis, Volume 88, Issue 1, Page 35-42, January 2023., 2023
Acetophenone azine (AA) induced skin allergies in humans. Based on in vitro/ in vivo testings derived from the AOP for skin sensitization, AA was positive both in h‑CLAT and KeratinoSens but negative in the LLNA. AA was considered a skin sensitizer. This was recently confirmed by its CLP classification.
Isabelle Manière, Alizée Aubert, Céline Dubois, Cécilia Solal, Jean‐Pierre Lepoittevin, Christophe Rousselle   +5 more
wiley   +1 more source

Network Model with Application to Allergy Diseases [PDF]

arXiv, 2023
We propose a new graphical model to describe the comorbidity of allergic diseases. We present our model in two versions. First, we introduce a generative model that correctly reflects the variables' causal relationship. Then we propose an approximation of the generative model by another misspecified model that is computationally more efficient and ...
arxiv  

Unbearable wearables [PDF]

, 2019
As wearable devices play an increasing role in the management of health and disease, adverse skin reactions to wearables have become more common. However, the management of allergic contact dermatitis is challenging and new treatment options more ...
Hayward, Elizabeth May, Leung, Thomas H, Rosenbach, Misha, Wei, Jenny J   +3 more
core  

Contact sensitizations in massage therapists with occupational contact dermatitis: Patch test data of the Information Network of Departments of Dermatology, 2008–2020

Contact Dermatitis, Volume 88, Issue 1, Page 43-53, January 2023., 2023
Hand dermatitis (91.4%) and allergic contact dermatitis (34.4%) were common in massage therapists with occupational dermatitis. Most frequent were sensitizations to fragrances/essential oils which were found in 54 (42.2%) of massage therapists and thus, more often than in other patients with occupational dermatitis.
Richard Brans, Claudia Schröder‐Kraft, Andrea Bauer, Elke Weisshaar, Christoph Skudlik, Johannes Geier, for the IVDK, Jürgen Grabbe, Katharina Siedlecki, Kerstin Strom, Margitta Worm, Dagmar Simon, Heinrich Dickel, Dieter Vieluf, André Koch, Nicola Wagner, Michal Gina, B. Kränke, Thomas Werfel, Knut Schäkel, Harald Löffler, Claudia Pföhler, Sibylle Schliemann, Guido Heine, Regina Treudler, Stefan Nestoris, Andreas Recke, Detlef Becker, Jan Nicolay, Rudolf Stadler, Franziska Rueff, Knut Brockow, Randolf Brehler, Ulrike Raap, Juliane Rieker‐Schwienbacher, Daniel Wilfinger, Johannes Weiß, Axel Trautmann, Claudia Lang   +38 more
wiley   +1 more source

Etiology of Allergic Contact Dermatitis based on Patch Test

Althea Medical Journal, 2017
Background: Allergic contact dermatitis is a type of contact dermatitis, whose  prevalence tends to increase every year. Patch test is an important diagnostic test to confirm the disease.
Dita Maulida Anggraini, Endang Sutedja, Achadiyani Achadiyani   +2 more
doaj   +1 more source

Uncertainty Quantification for Eosinophil Segmentation [PDF]

arXiv, 2023
Eosinophilic Esophagitis (EoE) is an allergic condition increasing in prevalence. To diagnose EoE, pathologists must find 15 or more eosinophils within a single high-power field (400X magnification). Determining whether or not a patient has EoE can be an arduous process and any medical imaging approaches used to assist diagnosis must consider both ...
arxiv