Results 91 to 100 of about 2,426,902 (210)

Extracellular DNA traps in allergic, infectzious, and autoimmune diseases

, 2013
Extracellular DNA traps are part of the innate immune response and are seen with many infectious, allergic, and autoimmune diseases. They can be generated by several different leukocytes, including neutrophils, eosinophils, and monocytes, as well as mast
Simon, Hans-Uwe, Yousefi, Shida, Simon, Dagmar   +2 more
core   +1 more source

Future research trends in understanding the mechanisms underlying allergic diseases for improved patient care [PDF]

, 2019
The specialties of allergy and clinical immunology have entered the era of precision medicine with the stratification of diseases into distinct disease subsets, specific diagnoses, and targeted treatment options, including biologicals and small molecules.
Wang, De Yun, Kari Nadeau, Akdis, Cezmi A, O’Hehir, Robyn E., Akdis, Cezmi A., O'Hehir, Robyn E, Fokkens, Wytske J., Nadeau, Kari, O’Mahony, Liam, De Yun Wang, Pfaar, Oliver, Luo Zhang, Torres, Maria J, Wytske J. Fokkens, Fokkens, Wytske J, Cezmi A. Akdis, Diamant, Zuzana, Zuzana Diamant, Liam O’Mahony, Traidl-Hoffmann, Claudia, Claudia Traidl‐Hoffmann, Robyn E. O’Hehir, Breiteneder, Heimo, Thomas Eiwegger, Oliver Pfaar, O'Mahony, Liam, Heimo Breiteneder, Maria J. Torres, Torres, Maria J., Zhang, Luo, Eiwegger, Thomas   +30 more
core   +1 more source

PCK2-Mediated PQBP1 Lactylation Promotes Asthmatic Inflammation through PRMT5 Inhibition

Research
Background: Asthma involves chronic inflammation linked to metabolic reprogramming, but how metabolites reshape epigenetics through posttranslational modifications remains unclear.
Qiaoyun Bai, Ningpo Ding, Rixin Feng, Fengxiang Shang, Zongqi Wang, Liangchang Li, Zhiguang Wang, Yihua Piao, Chongyang Wang, Yilan Song, Guanghai Yan   +10 more
doaj   +1 more source

Clinical and Laboratory Peculiarities of Chronic Active M. Epstein – I. Barr Virus Infection Course in Patients with Allergic Diseases

, 2018
Introduction. In case of weak or insufficient immune response, activation of chronic M. Epstein – I. Barr virus infection initiates different pathological disorders, one of which is allergy. Aim.
Zubchenko S., Chopyak V.
core   +1 more source

Seasonal Oxidative Stress and Airway Reactivity in Rhinitis: Distinct Patterns in Allergic vs. Non-allergic Individuals

Thoracic Research and Practice
OBJECTIVE: Rhinitis is a common upper airway disorder, classified as either allergic rhinitis (AR) or non-allergic rhinitis (NAR). While the association between air pollution and AR airway diseases has been well documented, its specific effects on NAR ...
Sümeyra Alan Yalım, Ayşe Füsun Kalpaklıoğlu, Ayşe Baççıoğlu   +2 more
doaj   +1 more source

Deficiency of DEK proto‐oncogene alleviates allergic rhinitis by inhibiting RhoA/Ezrin‐mediated mitochondrial fission

Animal Models and Experimental Medicine
Background Allergic rhinitis (AR) is a kind of immune disease mediated by IgE. We are intrigued by the potential role of DEK proto‐oncogene (DEK) in inflammation‐related diseases.
Longzhu Dai, Yongde Jin, Jingmei Chai, Jianing Yang, Jiangang Wang, Mu Chen, Liangchang Li, Chongyang Wang, Guanghai Yan   +8 more
doaj   +1 more source

Gene Therapy for Allergic Diseases

, 2010
Allergic diseases, such as allergic asthma, allergic rhinitis, atopic dermatitis, conjunctivitis, urticaria, food allergy, and/or anaphylaxis, are associated with the skewing of immune responses towards a T helper 2 ( TH2) phenotype, resulting in ...
莊雅惠;楊曜旭;江伯倫, CHUANG, YA-HUI;YANG, YAO-HSU;CHIANG, BOR-LUEN   +1 more
core   +1 more source

Autoimmune thyroid disease in inborn errors of immunity: a retrospective perspective

Orphanet Journal of Rare Diseases
Background Autoimmune thyroid diseases (AITDs) are among the most frequently reported autoimmune manifestations in individuals with inborn errors of immunity (IEIs).
Makbule Seda Bayrak Durmaz, Betul Ozdel Ozturk, Begum Gorgulu Akin, Fikriye Kalkan, Sadan Soyyiğit   +4 more
doaj   +1 more source

Validation of a food frequency questionnaire for children and adolescents aged 4 to 11 years living in Salvador, Bahia.

, 2012
OBJECTIVE: To assess the validity of a food frequency questionnaire (FFQ) by applying it to children and adolescents living in Salvador, Bahia. METHODS: The validity of this FFQ with 98 food items was investigated among 108 children and adolescents who ...
L. C. Rodrigues, M. S. Prado, S. D'Innocenzo, Dourado, L. S., Oliveira, NS, Barreto, M. L., C. A. S. T. Santos, Rodrigues, LC, A. M. O. Assis, Matos, SMA, Assis, A. M. O., Matos, S. M. A., Santos, CAST, L. S. Dourado, Prado, MS, D’lnnocenzo, S., M. L. Barreto, S. M. A. Matos, Dourado, LS, N. S. Oliveira, Prado, M. S., Oliveira, N. S., Assis, AMO, Barreto, ML, Santos, C. A. S. T., D'Innocenzo, S, Rodrigues, L. C.   +26 more
core   +1 more source

Polydatin Relieves Airway Remodeling by Inhibiting P2X7R–NLRP3‐Mediated Excessive Autophagy in Asthma

Immunity, Inflammation and Disease
Background Asthma is characterized by chronic airway inflammation and remodeling. Polydatin (PD), a natural compound, has shown anti‐inflammatory potential, but its role in asthma‐related airway remodeling and the underlying mechanisms involving the ...
Guangxing Li, Liangchang Li, Zhiguang Wang, Yihua Piao, Yilan Song, Li Li, Chang Xu, Xiaowan Li, Guanghai Yan   +8 more
doaj   +1 more source