Allergy, EarlyView.Nasal epithelial transcriptomics identified three cytokine‐associated epithelial immune programs linked to childhood asthma phenotypes. Age‐associated epithelial polarization shifted from IFN/type‐17‐associated toward type‐2‐associated programs after 3 years of age.
Constanze A. Jakwerth +71 more
wiley +1 more source
In Vivo Confocal Microscopy Revealed Alteration of Limbal Stem Cells and Sub-Basal Nerve Plexus in Allergic and Dry Eye-Related Ocular Surface Diseases. [PDF]
Transl Vis Sci TechnolWan X, Zhang K, Zhang Y, Mou Y, Huang X.
europepmc +1 more source
Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper
Allergy, EarlyView.ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres +19 more
wiley +1 more source
Update on the Physiopathology of Keratoconus. [PDF]
Med Sci (Basel)Barcelo-Canton RH +3 more
europepmc +1 more source
Pre‐Seasonal Treatment With Recombinant Carrier‐Based Birch Vaccine Improves Birch Pollen Allergy
Allergy, EarlyView.We conducted a two stage SCIT trial with GNR‐127 containing a recombinant fusion protein consisting of Bet v 1 and Mal d 1‐derived peptides fused to PreS from HBV. Stage 1 identified two safe maximum tolerated doses (40 μg and 80 μg). In the following Stage 2, five preseasonal injections were well tolerated, induced dose‐dependent allergen‐specific IgG,
Musa R. Khaitov +43 more
wiley +1 more source
Gut microbiota and pediatric eye diseases: current insights, mechanistic underpinnings, and future outlook. [PDF]
Front NutrChen G, Zhang Y, Zhang Y, Zhou Y.
europepmc +1 more source
Allergy, EarlyView.Using MASK‐air app data from 1042 users across 2690 weeks, this study compared the impact of regular versus as‐needed allergic rhinitis medication on symptom control and treatment satisfaction. Mixed‐effects linear regression models and sensitivity analyses revealed no significant differences between the two approaches, with results for oral ...
Bernardo Sousa‐Pinto +38 more
wiley +1 more source
Retrospective analysis of clinical efficacy and safety of fluorometholone combined with azelastine eye drops for seasonal allergic conjunctivitis. [PDF]
Front Med (Lausanne)Dai X, Yu J, Niu L, Chen XH.
europepmc +1 more source
Health-related quality of life and its determinants in children with allergic rhinitis. [PDF]
Front PediatrGuo L, Lu G, Wang X, Li Y.
europepmc +1 more source
Reproxalap - A Novel Treatment Option for Allergic Conjunctivitis - A Comprehensive Narrative Review. [PDF]
Health Sci RepMughal S +7 more
europepmc +1 more source