Results 31 to 40 of about 32,742 (288)

Neuroprotection in a Novel Mouse Model of Multiple Sclerosis [PDF]

, 2013
Multiple sclerosis is an immune-mediated, demyelinating and neurodegenerative disease that currently lacks any neuroprotective treatments. Innovative neuroprotective trial designs are required to hasten the translational process of drug development.
Coffey, P, Baker, MD, Coffey Pete, Jackson, SJ, Gavin Giovannoni, Baker David, Samuel J. Jackson (468645), Zubair Ahmed (9352), Jackson Samuel J., Zubair Ahmed, Ahmed, Z, Mark D Baker, Pete Coffey (422262), David Baker, Samuel J Jackson, Gavin Giovannoni (125820), Giovannoni Gavin, Munro Peter, Ahmed Zubair, Pete Coffey, David Baker (11642), Peter Munro (479715), Peter Munro, Lidster Katie, Baker Mark D., Baker, D, Lidster, K, Mark D. Baker (146531), Katie Lidster, Munro, P, Katie Lidster (479714), Giovannoni, G   +31 more
core   +1 more source

Long-term outcomes and risk factors for failure of glaucoma filtering surgery in eyes with vernal keratoconjunctivitis and steroid-induced glaucoma

Indian Journal of Ophthalmology, 2022
Purpose: To report outcomes and assess the risk factors for failure of trabeculectomy (trab), trabeculectomy with mitomycin-C (trabMMC), and combined trabeculectomy with cataract extraction (CT) in vernal keratoconjunctivitis (VKC) eyes with steroid ...
Sirisha Senthil, Harsha L Rao, Mohammed Hasnat Ali, Rashmi Krishnamurthy, Siddharth Dikshit, Nikhil Choudhari, Ramyasri Sastry, Chandrashekar Garudadri   +7 more
doaj   +1 more source

Comparison of ocular pathologies between children attending rural and urban schools in south india: A retrospective analysis

TNOA Journal of Ophthalmic Science and Research, 2022
Aims: To assess the differences in ocular morbidity with/without visual impairment between rural and urban school-going children using a two-step screening strategy. Methods: Data obtained by a hospital team from school camps conducted between the 1st of
Sabyasachi Chakrabarty, Meenakshi Ravindran, Madhavi Ramanatha Pillai, Shivkumar Chandrashekharan, Neelam Pawar, Mohammed Sithiq Uduman   +5 more
doaj   +1 more source

Ambient fine particulate matter and allergic symptoms in the middle-aged and elderly population: results from the PIFCOPD study

Respiratory Research, 2023
Background The associations between short- and long-term exposure to ambient fine particulate matter with an aerodynamic diameter ≤ 2.5 µm (PM2.5) and allergic symptoms in middle-aged and elderly populations remain unclear, particularly in China, where ...
Shanshan Wei, Jiping Liao, Tao Xue, Kunyao Yu, Xiuhua Fu, Ruiying Wang, Xiaomin Dang, Cheng Zhang, Hua Qiao, Shujuan Jiang, Jianhong Xiao, Lixia Dong, Jinzhi Yin, Xixin Yan, Weihua Jia, Guifang Zhang, Rui Chen, Bo Zhou, Beibei Song, Jing Li, Mengyu Yin, Lina Zhang, Liping Xie, Shaochen Dong, Jian Sun, Peng Gao, Bifang Miao, Wei Li, Lan He, Qian Ning, Limin Zhao, Hengyi Liu, Han Cao, Guangfa Wang   +33 more
doaj   +1 more source

Executive summary: Japanese guidelines for allergic conjunctival diseases 2021

Allergology International, 2022
Allergic conjunctival disease (ACD) is an inflammatory disease of the conjunctiva that is mainly caused by type I hypersensitivity response to allergens and accompanied by subjective symptoms and other findings induced by antigens.
Dai Miyazaki, Atsuki Fukushima, Eiichi Uchio, Jun Shoji, Kenichi Namba, Nobuyuki Ebihara, Etsuko Takamura, Ken Fukuda, Akira Matsuda, Shigeki Okamoto, Kazumi Fukagawa, Hiroshi Fujishima, Shigeaki Ohno, Yuichi Ohashi   +13 more
doaj   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Investigating the role of allergic contact dermatitis in residual ocular surface disease on dupilumab (ROSDD)

International Journal of Women's Dermatology, 2019
Background: The mechanisms underlying eye-related complications with dupilumab are poorly understood. Objective: This study aimed to determine the incidence and characteristics of ocular complications with dupilumab and the prevalence of comorbid ...
Jodie Raffi, BA, Raagini Suresh, BS, Harvey Fishman, MD, PhD, Nina Botto, MD, Jenny E. Murase, MD   +4 more
doaj   +1 more source

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah   +17 more
wiley   +1 more source

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

Hepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F. Simões, José Teixeira, Liana C. Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E. Castro, Paulo J. Oliveira, Carina Prip‐Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M. P. Rodrigues   +16 more
wiley   +1 more source

A Comprehensive Literature Review of Allergic Conjunctivitis

, 2022
Allergic disease is a complex disease caused by a combination of genetic and environmental factors. Allergic diseases are on the rise, affecting about 30% to 40% of the world\u27s population. In addition to a decrease in quality of life, this disease can
Cahyana, Nugraha Wahyu
core   +2 more sources