Results 241 to 250 of about 217,585 (300)

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

open access: yesAllergy, EarlyView.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque   +5 more
wiley   +1 more source

Dendritic Cell α‐Ketoglutarate Regulates Tfh Polarization in Allergy

open access: yesAllergy, EarlyView.
Allergen induces a dendritic cell metabolism shift toward glutaminolysis with α‐ketoglutarate as a regulator of Tfh subset polarization. Glutaminolysis is required for DC allergen uptake, co‐stimulatory molecule expression, and CLR expression. Modulation of glutaminolysis, JmjD3 histone demethylation, or HIF‐1α degradation alters Tfh polarization and ...
Anuj Tharakan   +16 more
wiley   +1 more source

Replication of genomewide associations with allergic sensitization and allergic rhinitis

open access: yesAllergy: European Journal of Allergy and Clinical Immunology, 2014
Three genomewide metastudies have recently reported associations with self-reported allergic rhinitis and allergic sensitization. The three studies together identified a set of 37 loci but showed low concordance. This study investigates the reproducibility of the detected single nucleotide polymorphism (SNP) associations in an extensively characterized
D, Nilsson   +7 more
exaly   +4 more sources

Staphylococcus aureus enterotoxin sensitization is associated with allergic poly‐sensitization and allergic multimorbidity in adolescents

open access: yesAllergy: European Journal of Allergy and Clinical Immunology, 2017
Background: Staphylococcus aureus (S. aureus) carriage and sensitization to S. aureus enterotoxins (SEs) have been associated with allergic diseases. From the Tromso Study Fit Futures 2, we have previously shown an association between S.
Martin Sørensen, Claus Bachert
exaly   +2 more sources
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The role of lectins in allergic sensitization and allergic disease

Journal of Allergy and Clinical Immunology, 2013
Allergic diseases are a global public health issue affecting millions of persons around the world. However, full understanding of the molecular basis of this group of chronic inflammatory disorders remains rather elusive. Recently, the role of carbohydrates on allergens and their counterstructures on antigen-presenting cells (lectins) have been ...
Fabián, Salazar   +3 more
openaire   +2 more sources

Effect of parasitosis on allergic sensitization in rats sensitized with ovalbumin: Interaction between parasitosis and allergic sensitization

Advances in Therapy, 2007
Some helminthic infections, especially nematode infections, may behave as allergens and induce allergic sensitization. In this study, the investigators explored whether infections with Syphacia muris and Aspiculuris tetraptera have any effect on the development of allergen-induced cytokine responses and serum total immunoglobulin E (IgE) levels in ...
Demirturk, Nese   +6 more
openaire   +2 more sources

Allergic contact sensitivity to quinophthalone

Contact Dermatitis, 1989
A 73‐year‐old patient, diagnosed as having seborrheic dermatitis, was patch tested with his hair preparations. The hair stick gave a positive reaction. Among its ingredients, D & C Yellow No. 11, from 0.0001% to 0.1%, and perfume showed positive reactions. D & C Yellow No. 11 was found to consist only of quinophthalone by chemical analyses. The
H, Komamura   +4 more
openaire   +2 more sources

Trends in allergic contact sensitization

Contact Dermatitis, 1988
A standard patch test series was tested for 7 years (1977–1983) in a total of 11,962 patients. The annual frequency of positive reactions to the compounds tested was assessed for the total and for males and females separately. During the observation period, there were significant increases in positive reactions in the total group from 6.2% to 12.7% for
R, Gollhausen   +4 more
openaire   +2 more sources

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