Results 211 to 220 of about 2,787,448 (332)
ABSTRACT Pyruvate kinase (PK) is a key enzyme involved in the final step of glycolysis, essential to produce adenosine triphosphate (ATP). Relatively decreased red blood cell (RBC) PK activity (reflected by a lower PK/hexokinase [HK] ratio) and PK thermostability (PK activity after exposure to heat) were recently identified as pathophysiological ...
M. J. M. Traets+17 more
wiley +1 more source
Outpatient Consultation in Allergy/Immunology [PDF]
Jörg Dietrich+2 more
openalex +1 more source
ABSTRACT Transplant‐associated thrombotic microangiopathy (TA‐TMA) is an endothelial dysfunction syndrome observed after allogeneic hematopoietic cell transplant (alloHCT). Our aim was to externally validate the impact of high‐risk features on the clinical outcomes of adult patients meeting the updated TA‐TMA harmonizing criteria. Between 2005 and 2022,
Aldo A. Acosta‐Medina+19 more
wiley +1 more source
TP53 ‐Mutated Myeloid Neoplasms: 2024 Update on Diagnosis, Risk‐Stratification, and Management
ABSTRACT Alterations in the tumor suppressor gene TP53 are common in human cancers and are associated with an aggressive nature. Approximately 8%–12% of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) harbor TP53 mutations (TP53 mut) and present immense challenges due to inherent chemoresistance and poor outcomes.
Mithun Vinod Shah+2 more
wiley +1 more source
Clinical competencies in allergy and immunology: Results of a graduate survey
James T. Li+3 more
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Testing of IgG and IgG4 to foods is not recommended / Position of the German Society of Allergy and Clinical Immunology (DGAKI) a , the Physician's Society of German Allergists (ÄDA) and the Society of Pediatric Allergy and Environmental Medicine (GPA), the Austrian Society of Allergy and Immunology (ÖGAI) and the Swiss Society of Allergy and Immunology (SGAI) after Adoption of the Task Force Report b of the European Academy of Allergy and Clinical Immunology (EAACI) [PDF]
Jörg Kleine‐Tebbe+19 more
openalex +1 more source
ABSTRACT With the recent publication of new classification systems of hematopoietic neoplasms, understanding how recognition of disease entities has occurred over time and the subsequent development of formal disease classifications is of importance. This review focuses on the early recognition of myeloid disorders, especially chronic myeloid disorders,
Daniel A. Arber, Attilio Orazi
wiley +1 more source