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Allogeneic hematopoietic stem cell transplantation for myelofibrosis

Current Opinion in Hematology, 2006
This review summarizes the current status and new developments in allogeneic hemopoietic stem cell transplantation strategies for patients with myelofibrosis with myeloid metaplasia, focusing on novel concepts of allogeneic transplantation with reduced-intensity conditioning.No substantial progress has been made in the conventional management of ...
Giovanni, Barosi, Andrea, Bacigalupo
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Immunobiology of Allogeneic Hematopoietic Stem Cell Transplantation

Annual Review of Immunology, 2007
Allogeneic hematopoietic stem cell transplantation (HSCT) has evolved into an effective adoptive cellular immunotherapy for the treatment of a number of cancers. The immunobiology of allogeneic HSCT is unique in transplantation in that it involves potential immune recognition and attack between both donor and host.
Lisbeth A, Welniak   +2 more
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Complications of Allogeneic Hematopoietic Stem Cell Transplantation

Cancer Investigation, 2014
Infection, graft-versus-host disease (GVHD), and to a lesser extent sinusoidal obstructive syndrome (SOS) represent the major causes of morbidity and mortality in patients undergoing allogeneic hematopoietic stem cell transplantation (AHSCT). During the last decade, progress in prevention and treatment of these complications led to improvement in the ...
El-Amm, Joelle   +5 more
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Dendritic cells in allogeneic hematopoietic stem cell transplantation

Leukemia & Lymphoma, 2005
In allogeneic hematopoietic stem cell transplantation (SCT), dendritic cells (DCs) as the most potent antigen-presenting cells play a central role in the development of acute and chronic graft-vs-host disease (GVHD), in graft-vs-leukemia or -malignancy reactions and in fighting infectious complications.
D, Nachbaur, B, Kircher
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Allogenic submandibular gland transplantation following hematopoietic stem cell transplantation

Journal of Cranio-Maxillofacial Surgery, 2013
Autologous submandibular gland transfer for treatment of progressive dry eye symptoms requires a functionally intact submandibular gland. In cases of total function loss of both lacrimal and submandibular glands this procedure has to be modified. Here we report on the first two cases of the allogenic transplantation of a submandibular gland to treat ...
Hans-Christian, Jacobsen   +5 more
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Ocular Findings after Allogeneic Hematopoietic Stem Cell Transplantation

Ophthalmology, 2009
To study the incidence, causes, and outcome of major ocular complications in patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT).Retrospective, noncomparative, observational clinical study.The study included a total of 620 patients who underwent allogeneic HSCT in the period from 1997 to 2007 at King Faisal Specialist Hospital
Khalid F, Tabbara   +9 more
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[Allogeneic hematopoietic stem cell transplantation].

La Revue du praticien, 2009
Allogeneic hematopoietic stem cell transplantation is a curative option in different hematologic malignancies. This benefit is traditionally based on the immune anti-tumour effect mediated by the allogeneic immune effectors derived from the graft, usually called "graft versus leukemia".
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[Allogeneic hematopoietic stem cell transplantations].

Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine, 2011
Allogeneic hematopoietic stem cell transplantation is the most widely used form of immunotherapy. The allogeneic immune effectors infused with the graft can recognize and eradicate the patients' tumoral cells. The curative potential of allogeneic hematopoietic stem cell transplantation is classically based on two mechanisms: the conditioning myelo ...
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Allogeneic hematopoietic stem cell transplantation for neuromyelitis optica

Annals of Neurology, 2014
Neuromyelitis optica is a rare neurological autoimmune disorder characterized by a poor prognosis. Immunosuppression can halt disease progression, but some patients are refractory to multiple treatments, experiencing frequent relapses with accumulating disability.
Greco R   +19 more
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Nonmyeloablative therapy and allogeneic hematopoietic stem cell transplantation

Experimental Hematology, 2003
The toxicities associated with conventional myeloablative therapy and allogeneic hematopoietic stem cell transplantation (SCT) limit the use of this potentially curative approach to relatively healthy young patients. The risk of treatment-related morbidity and mortality with conventional allogeneic SCT ranges from 10% to 50%, depending on the age of ...
Imad A, Tabbara, Richard M, Ingram
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