Results 351 to 360 of about 256,813 (405)

Acute Myeloid Leukemia: 2025 Update on Diagnosis, Risk‐Stratification, and Management

open access: yesAmerican Journal of Hematology, Volume 100, Issue 5, Page 860-891, May 2025.
ABSTRACT Disease Overview Acute myeloid leukemia (AML) is a bone marrow stem cell cancer that is often fatal despite available treatments. Diagnosis, risk assessment, monitoring, and therapeutic management of AML have changed dramatically in the last decade due to increased pathophysiologic understanding, improved assessment technology, and the ...
Shai Shimony   +2 more
wiley   +1 more source

Role of cytomegalovirus reactivation on relapse after allogeneic hematopoietic stem cell transplantation in acute lymphoblastic leukemia. [PDF]

open access: yesClin Hematol Int
Mekni S   +10 more
europepmc   +1 more source

Clinical Outcomes and Treatment Strategies of Adult Transplant‐Associated Thrombotic Microangiopathy: External Validation of Harmonizing Definitions and High‐Risk Criteria

open access: yesAmerican Journal of Hematology, Volume 100, Issue 5, Page 830-839, May 2025.
ABSTRACT Transplant‐associated thrombotic microangiopathy (TA‐TMA) is an endothelial dysfunction syndrome observed after allogeneic hematopoietic cell transplant (alloHCT). Our aim was to externally validate the impact of high‐risk features on the clinical outcomes of adult patients meeting the updated TA‐TMA harmonizing criteria. Between 2005 and 2022,
Aldo A. Acosta‐Medina   +19 more
wiley   +1 more source

Substitution of Glutamic Acid at Position 71 of DRβ1*04:01 and Collagen‐Specific Tolerance Without Alloreactivity

open access: yesArthritis &Rheumatology, Volume 77, Issue 5, Page 526-535, May 2025.
Objective The DRB1 locus is strongly associated with both susceptibility and resistance to rheumatoid arthritis (RA). DRB1 alleles encoding the VKA or VRA epitope in positions 11, 71, and 74 confer the highest risk of developing RA, whereas the allele encoding VEA is protective.
Vibha Jha   +10 more
wiley   +1 more source

Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation for Diffuse Cutaneous Systemic Sclerosis: Identifying Disease Risk Factors for Toxicity and Long‐Term Outcomes in a Prospective, Single‐Arm Trial

open access: yesArthritis &Rheumatology, Volume 77, Issue 5, Page 571-581, May 2025.
Objective Two randomized trials for patients with diffuse systemic sclerosis (SSc) demonstrated an overall survival (OS) and event‐free survival (EFS) advantage of autologous hematopoietic stem cell transplantation (AHSCT) using CD34+ selected peripheral blood stem cells (PBSCs) compared with monthly cyclophosphamide (CY).
George E. Georges   +16 more
wiley   +1 more source

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