Results 101 to 110 of about 193,745 (246)

Multimaterial Triphasic Scaffold Replicates Enthesis Microenvironment to Modulate Early Cell Responses

open access: yesAdvanced NanoBiomed Research, EarlyView.
A bioinspired triphasic scaffold integrating 3D printed polycaprolactone and electrospun poly(lactic‐co‐glycolic acid) is developed to replicate the organization of the tendon‐to‐bone enthesis. Cyclic mechanical stimulation induces spatially defined cell morphology and lineage‐related gene expression in human mesenchymal stem cells, highlighting the ...
Ginevra Pegollo   +7 more
wiley   +1 more source

A Doxorubicin‐Loaded Liposomes Baghdadite System for Localized Osteosarcoma Therapy and Bone Regeneration

open access: yesAdvanced NanoBiomed Research, EarlyView.
This study presents a multifunctional Baghdadite ceramic implant integrating doxorubicin‐loaded liposomes via ion‐assisted plasma polymer coating for localized osteosarcoma therapy. The platform enables drug retention, sustained release, tumor cell inhibition, osteoconductivity, and antibacterial activity, offering a mechanically robust strategy for ...
Sally Kortam   +8 more
wiley   +1 more source

Combined Superior Capsular Reconstruction and Lower Trapezius Transfer Using an Achilles Tendon Allograft Show Better Clinical Outcomes and Lower Graft Tear Rates Versus Isolated Superior Capsular Reconstruction for Chronic Posterosuperior Irreparable Massive Rotator Cuff Tears With Severe Fatty Infiltration in the Infraspinatus

open access: yesArthroscopy, EarlyView.
Purpose To compare the surgical outcomes of superior capsular reconstruction (SCR) combined with lower trapezius transfer (LTT) using an Achilles tendon allograft versus isolated SCR for the treatment of posterosuperior irreparable massive rotator cuff tears with severe infraspinatus fatty infiltration (Goutallier grades 3‐4).
Hui Ben   +3 more
wiley   +1 more source

NONSTRAIN SEAMLESS HERNIOPLASTY TRABUCCO PERFORMED IN ELDERLY AND SENILE PATIENTS WITH THE INGUINAL HERNIA

open access: yesВестник хирургии имени И.И. Грекова, 2018
An analysis of results of «nonstrain» methods of hernioplasty is presented in the elderly and senile patients with the pronounced accompanying pathology in the overwhelming majority of patients (93,5%).
R. T. Medzhidov   +2 more
doaj   +1 more source

Partial Repair and Superior Capsular Reconstruction Both Improve Outcomes for Irreparable Posterosuperior Rotator Cuff Tears: A Systematic Review

open access: yesArthroscopy, EarlyView.
Purpose To synthesize patient‐reported outcome measures, failure rates, and mobility parameters for comparison of partial repair versus superior capsular reconstruction (SCR) in the treatment of irreparable posterosuperior rotator cuff tears. Methods EMBASE, OVID Medline, and Emcare were searched from database inception to November 2024 for studies on ...
Marc Daniel Bouchard   +5 more
wiley   +1 more source

The role of cryopreservation in the biomechanical properties of the intervertebral disc [PDF]

open access: yesEuropean Cells & Materials, 2011
Implantation of intervertebral disc (IVD) allograft or tissue engineered disc constructs in the spine has emerged as an alternative to artificial disc replacement for the treatment of severe degenerative disc disease (DDD).
SKL Lam   +5 more
doaj  

Serum Proteomic Signatures of Rheumatoid Arthritis Risk and Response: Analysis of a Rheumatoid Arthritis Interception Trial

open access: yesArthritis &Rheumatology, EarlyView.
Objective Our study objective was to identify serum protein signatures associated with progression to rheumatoid arthritis (RA) and response to abatacept in at‐risk individuals. Methods A total of 440 serum samples from 118 APIPPRA (Arthritis Prevention In the Preclinical Phase of RA with Abatacept) study participants were selected from baseline to RA ...
Marianna Jasenecova   +9 more
wiley   +1 more source

Arthroscopic Lateral Collateral Ligament Reconstruction With Tendon Graft in High‐Grade Atraumatic Posterolateral Rotatory Instability in Elbows

open access: yesArthroscopy Techniques, EarlyView.
Abstract Lateral collateral ligament imbrication has been reported to yield good results in patients with atraumatic posterolateral rotatory instability who do not respond to conservative treatment. In cases of high‐grade instability, however, achieving adequate ligament tension can be difficult, and excessive tightening often contributes to ...
Cholawish Chanlalit   +2 more
wiley   +1 more source

The Interactions of T Cells with Myeloid-Derived Suppressor Cells in Peripheral Blood Stem Cell Grafts

open access: yesCells
The interaction of myeloid-derived suppressor cells (MDSCs) with T cells within G-CSF-mobilized peripheral blood stem cell (PBSC) grafts in patients undergoing autologous or allogeneic hematopoietic stem cell transplantation remains to be elucidated ...
Qingdong Guan   +7 more
doaj   +1 more source

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk   +5 more
wiley   +1 more source

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