Chronic Allograft Nephropathy [PDF]
Long-term survival of kidney transplants (renal allografts) has changed little during the past decade, despite dramatic improvements in short-term survival. Most late renal allograft loss, other than that associated with the death of the patient, has been attributed to progressive renal dysfunction, termed "chronic allograft nephropathy" (or CAN), a ...
Torras Ambròs, Joan +2 more
openaire +4 more sources
Ticiana De Francesco,1,2 Tsontcho Ianchulev,3 Douglas J Rhee,4 Ronald C Gentile,3,5 Louis R Pasquale,3 Iqbal Ike K Ahmed1,6,7 1John A. Moran Eye Center, University of Utah, Salt Lake City, UT, USA; 2Clinica de Olhos De Francesco, Fortaleza, Brazil ...
De Francesco T +5 more
doaj +2 more sources
CD160Ig fusion protein targets a novel costimulatory pathway and prolongs allograft survival. [PDF]
CD160 is a cell surface molecule expressed by most NK cells and approximately 50% of CD8(+) cytotoxic T lymphocytes. Engagement of CD160 by MHC class-I directly triggers a costimulatory signal to TCR-induced proliferation, cytokine production and ...
Freeman, Gordon +46 more
core +1 more source
Human Acellular Dermal Allograft Patch on Traumatic Tympanic Membrane Perforation
BACKGROUND: This study aimed to investigate the outcome of using the human acellular dermal allograft patch compared with the conventional paper patch in traumatic tympanic membrane perforation.
Lee, Dong-Han +5 more
core +1 more source
Concomitant Polyoma BK Virus and West Nile Virus in Renal Allografts
Surveillance of the renal allograft recipient is essential when monitoring renal function to detect the early onset of rejection and alter therapeutic treatments to treat acute rejection or other causes and improve long-term graft function.
Riddhish T. Sheth +6 more
doaj +1 more source
Reduced CD40L expression on ex vivo activated CD4+T-lymphocytes from patients with excellent renal allograft function measured with a rapid whole blood flow cytometry procedure [PDF]
Background: The CD40-CD40L (CD154) costimulatory pathway plays a critical role in the pathogenesis of kidney allograft rejection. In renal transplant biopsies, CD4+ CD40L+ graft-infiltrating cells were detected during chronic rejection in contrast to ...
Lederer, Stephan R. +5 more
core +1 more source
Background: Solid organ rejection post-SARS-CoV-2 vaccination or COVID-19 infection is extremely rare but can occur. T-cell recognition of antigen is the primary and central event that leads to the cascade of events that result in rejection of a ...
Saad Alhumaid +28 more
doaj +1 more source
Learning Curve of Minimally Invasive C1-C2 Trans-articular Screw Fixation (MIS-TAS): Over A Period of Five Years [PDF]
Objective To evaluate the learning curve associated with minimally invasive surgery (MIS) in posterior C1-C2 trans-articular (TAS) screw fixation based on surgical and clinical parameters.
Saijyot Raut +4 more
doaj +1 more source
Morphometric Measurements of Posterior Cruciate Ligament and its Clinical Implications: A Cadaveric Cross-sectional Study [PDF]
Introduction: Posterior Cruciate Ligament (PCL) is a band like structure which tightly adheres to femur and tibia with collagen fibres. It is considered as an active and primary stabiliser of the knee joint and it acts as the principal restraint against ...
Abhinav Kumar Mishra, Hetal Vaishnani
doaj +1 more source
Non-invasive monitoring of renal transplant recipients: Urinary excretion of soluble adhesion molecules and of the complement-split product C4d [PDF]
Background: The number of inducible adhesion molecules known to be involved in cell-mediated allograft rejection is still increasing. In addition, recent data describe complement activation during acute humoral allograft rejection.
Lederer, Stephan R. +5 more
core +1 more source

