Results 101 to 110 of about 484,803 (308)

Respiratory metapneumoviral infection without co-infection in association with acute and chronic lung allograft dysfunction

Journal of Inflammation Research, 2015
Amrita DosanjhDepartment of Pediatrics, Rady Children’s Hospital, San Diego, CA, USABackground: Metapneumoviral respiratory infection is a community-acquired respiratory viral (CARV) infection. Lung transplantation recipients exposed to CARV are at
Dosanjh A
doaj  

A Subset of Pro‐inflammatory CXCL10+ LILRB2+ Macrophages Derives From Recipient Monocytes and Drives Renal Allograft Rejection

Advanced Science, EarlyView.
This study uncovers a recipient‐derived monocyte‐to‐macrophage trajectory that drives inflammation during kidney transplant rejection. Using over 150 000 single‐cell profiles and more than 850 biopsies, the authors identify CXCL10+ macrophages as key predictors of graft loss.
Alexis Varin, Jovanne Palvair, Lennie Messager, Jamal Bamoulid, Jasper Callemeyn, Mélanie Chaintreuil, Ludivine Dal Zuffo, Didier Ducloux, Imane Farhat, Mathieu Legendre, Laurent Martin, Florian Renosi, Xavier Roussel, Thibaut Vaulet, Maarten Naesens, Claire Tinel, Baptiste Lamarthée   +16 more
wiley   +1 more source

Using a combination of biomarkers to monitor allograft dysfunction in lung transplant recipients

Frontiers in Transplantation
Allograft dysfunction is a major limitation of survival in organ transplant recipients including those who have received lung transplantation. Early detection of allograft dysfunction is thus crucial to improve outcomes in these patients.
Zein Kattih, Shambhu Aryal
doaj   +1 more source

The role of CD8+ T cells during allograft rejection

Brazilian Journal of Medical and Biological Research, 2002
Organ transplantation can be considered as replacement therapy for patients with end-stage organ failure. The percent of one-year allograft survival has increased due, among other factors, to a better understanding of the rejection process and new ...
V. Bueno, J.O.M. Pestana
doaj   +1 more source

Pathologic analysis of liver transplantation for primary biliary cirrhosis [PDF]

, 1988
A retrospective histopathologic review of all pathologic specimens from 394 adult liver transplant patients was undertaken with clinical correlation to determine if primary biliary cirrhosis has affected the posttrans‐plant course compared to all other ...
Ballardini, Baum, Berg, Bernuau, Demetris, Demetris, Demetris, Demetris, Detre, Epstein, Epstein, Esquivel, Fennell, Fung, Haagsma, Iwatsuki, James, MacSween, McFarlane, McFarlane, Neuberger, Popper, Portmann, Portmann, Portmann, Vento   +25 more
core   +1 more source

Endogenous Memory CD8 T Cells Directly Mediate Cardiac Allograft Rejection

American Journal of Transplantation, 2014
Differences in levels of environmentally induced memory T cells that cross‐react with donor MHC molecules are postulated to account for the efficacy of allograft tolerance‐inducing strategies in rodents versus their failure in nonhuman primates and human
Charles A. Su, Charles A. Su, S. Iida, T. Abe, R. Fairchild, R. Fairchild   +5 more
semanticscholar   +1 more source

Risk Factors for Small‐for‐Size Syndrome Grade B/C After Simultaneous Splenectomy in Adult Living‐Donor Liver Transplantation

Annals of Gastroenterological Surgery, EarlyView.
In a single‐center cohort of 577 adult LDLT recipients who underwent simultaneous splenectomy, clinically significant SFSS grade B/C (ILTS‐iLDLT‐LTSI 2023) occurred in 18.2% and was associated with inferior graft survival. Multivariate analysis identified MELD ≥ 30, NLR ≥ 4.5, and donor age ≥ 50 years as independent risk factors, which risk rising ...
Kyohei Yugawa, Takeo Toshima, Shinji Itoh, Takashi Motomura, Shohei Yoshiya, Norifumi Iseda, Tomoharu Yoshizumi   +6 more
wiley   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Differentiation of acute versus chronic skin rejection in a rodent model of vascularized composite allotransplantation

Frontiers in Immunology
BackgroundVascularized composite allografts (VCA) have evolved to be a potential option in complex reconstructive surgery. However, managing acute and chronic allograft rejection remains challenging.
Julia Thomé, Maike Lind, Maxime Schmitt, Laura Schneider, Jurij Kiefer, Jurij Kiefer, Rebecca Schäfer, Emma Freise, Thierry Christmann, Sheena Kreuzaler, Branislav Kollár, Steffen U. Eisenhardt   +11 more
doaj   +1 more source

Intestinal transplantation under tacrolimus monotherapy after perioperative lymphoid depletion with rabbit anti-thymocyte globulin (thymoglobulin®) [PDF]

, 2005
Modifications in the timing and dosage of immunosuppression can ameliorate the morbidity and mortality that has prevented widespread use of intestinal transplantation (ITx) in children.
Abu-Elmagd, K, Bond, GJ, Macedo, C, Mazariegos, GV, Murase, N, Peters, J, Reyes, J, Sindhi, R, Starzl, TE   +8 more
core   +1 more source