Results 11 to 20 of about 484,803 (308)

The Immunological Basis of Liver Allograft Rejection

Frontiers in Immunology, 2020
Liver allograft rejection remains a significant cause of morbidity and graft failure in liver transplant recipients. Rejection is caused by the recognition of non-self donor alloantigens by recipient T-cells.
Vincenzo Ronca, Vincenzo Ronca, Vincenzo Ronca, Grace Wootton, Chiara Milani, Owen Cain   +5 more
doaj   +2 more sources

Resident memory T cells form during persistent antigen exposure leading to allograft rejection

Science immunology, 2021
Recipient effector T cells differentiate into functional tissue-resident memory T cells, causing graft rejection after kidney transplantation. Memories of rejection Long-term graft survival after organ transplantation can be hindered by immune-mediated ...
Khodor I. Abou-Daya, R. Tieu, Daqiang Zhao, R. Rammal, F. Sacirbegovic, Amanda L. Williams, W. Shlomchik, M. Oberbarnscheidt, Fadi G Lakkis   +8 more
semanticscholar   +1 more source

Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII+ innate immune cells in rejection

medRxiv, 2022
Rejection remains the main cause of premature graft loss after kidney transplantation, despite the use of potent immunosuppression. This highlights the need to better understand the composition and the interactions of the alloreactive inflammatory ...
B. Lamarthée, J. Callemeyn, Y. Van Herck, A. Antoranz, D. Anglicheau, Patrick Boada, J. Becker, Tim Debyser, F. De Smet, K. De Vusser, Maëva Eloudzeri, A. Franken, W. Gwinner, P. Koshy, D. Kuypers, D. Lambrechts, P. Marquet, V. Mathias, M. Rabant, M. Sarwal, A. Senev, T. Sigdel, B. Sprangers, O. Thaunat, C. Tinel, Thomas van Brussel, A. V. Van Craenenbroeck, E. Van Loon, T. Vaulet, F. Bosisio, M. Naesens   +30 more
semanticscholar   +1 more source

Allograft rejection in kidney transplantation – A retrospective study of impact on graft and patient outcome

Indian Journal of Transplantation, 2022
Background: Renal allograft rejection is a major cause of graft dysfunction, and it is a predictor of long-term allograft loss. Advances in immunosuppression have decreased the influence of acute rejection on graft survival.
M P Shamsudheen, Abid Kuchay, Vijay Chander Gupta, Isha Tiwari, Raja Karthik, Uttara Das, Swarnalatha Guditi, Gangadhar Taduri   +7 more
doaj   +1 more source

The Use of Donor-Derived Cell-Free DNA for Assessment of Allograft Rejection and Injury Status

Journal of Clinical Medicine, 2020
Patient monitoring after kidney transplantation (KT) for early detection of allograft rejection remains key in preventing allograft loss. Serum creatinine has poor predictive value to detect ongoing active rejection as its increase is not sensitive, nor ...
C. Thongprayoon, Pradeep K Vaitla, Iasmina M. Craici, Napat Leeaphorn, P. Hansrivijit, S. Salim, T. Bathini, Franco H. Cabeza Rivera, W. Cheungpasitporn   +8 more
semanticscholar   +1 more source

Is rejection a diffuse or localized process in small-bowel transplantation? [PDF]

, 1994
Utilization of endoscopy to both visualize and selectively biopsy an intestinal allograft has become the standard for early recognition and treatment of intestinal allograft rejection.
A Jain, A. Gurakar, B Banner, CC Inshan Clark, D. H. Van Thiel, E. Frezza, H. I. Wright, K Abu-Elmagd, K Nakamura, K Nakamura, KM Abu-Elmagd, M. Balkan, P Schroeder, S Todo, S Todo, S Todo, S Todo, S. Fagiuoli, S. Todo, T. E. Starzl, T. Hassanein   +20 more
core   +1 more source

Non-invasive monitoring of renal transplant recipients: Urinary excretion of soluble adhesion molecules and of the complement-split product C4d [PDF]

, 2003
Background: The number of inducible adhesion molecules known to be involved in cell-mediated allograft rejection is still increasing. In addition, recent data describe complement activation during acute humoral allograft rejection.
Friedrich, N., Getto, R., Lederer, Stephan R., Regenbogen, C., Sitter, Thomas, Toepfer, Marcel   +5 more
core   +1 more source

Hyperlipidemia and Allograft Rejection [PDF]

Current Transplantation Reports, 2019
Advances in the development of immunosuppressive drug regimens have led to impressive survival rates in the year following organ transplantation. However rates of long-term graft dysfunction remain undesirably high. Recently it has been shown that co-morbidities in the patient population may affect graft survival.
Jessamyn, Bagley, Linus, Williams, Michael, Hyde, Christian Rosa, Birriel, John, Iacomini   +4 more
openaire   +2 more sources

Kidney Allograft Function Is a Confounder of Urine Metabolite Profiles in Kidney Allograft Recipients

Metabolites, 2021
Noninvasive biomarkers of kidney allograft status can help minimize the need for standard of care kidney allograft biopsies. Metabolites that are measured in the urine may inform about kidney function and health status, and potentially identify rejection
Karsten Suhre, Darshana M. Dadhania, John Richard Lee, Thangamani Muthukumar, Qiuying Chen, Steven S. Gross, Manikkam Suthanthiran   +6 more
doaj   +1 more source

Proteomics for rejection diagnosis in renal transplant patients: where are we now? [PDF]

, 2016
Rejection is one of the key factors that determine the long-term allograft function and survival in renal transplant patients. Reliable and timely diagnosis is important to treat rejection as early as possible.
Gwinner, Wilfried, Husi, Holger, Marx, David, Metzger, Jochen   +3 more
core   +1 more source