Results 31 to 40 of about 484,803 (308)

Humoral Rejection of Organ Allografts [PDF]

open access: yesAmerican Journal of Transplantation, 2005
In recent years, the deleterious clinical consequences of recipient de novo alloantibody production against HLA antigens from human organ allografts have been extensively investigated. In kidney transplantation, the identification of the complement C4d fragment in peritubular capillaries as a specific marker for humoral rejection has helped to define ...
Moll, Solange, Pascual, Manuel
openaire   +3 more sources

Circulating mitochondria in organ donors promote allograft rejection

open access: yesAmerican Journal of Transplantation, 2019
The innate immune system is a critical regulator of the adaptive immune responses that lead to allograft rejection. It is increasingly recognized that endogenous molecules released from tissue injury and cell death are potent activators of innate ...
Liwen Lin   +8 more
semanticscholar   +1 more source

The significance of cytologic examination of urine in the diagnosis of renal allograft dysfunction [PDF]

open access: yesVojnosanitetski Pregled, 2003
Background. This paper presents our experience with cytologic examination of urine in diagnosing renal allograft dysfunction. Methods. The study group included 23 patients with renal allograft dysfunction, selected from 56 patients who underwent renal ...
Tatomirović Željka   +5 more
doaj   +1 more source

COVID-19 vaccination and corneal allograft rejection- a review

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
AimTo provide a comprehensive literature review on the perceived correlation between COVID-19 vaccination and corneal allograft rejection, and to characterize risk factors, time course, graft outcomes and proposed immunological basis.MethodsA literature ...
Natalie E. Allen   +2 more
doaj   +1 more source

Experimental rat models of chronic allograft nephropathy: a review [PDF]

open access: yes, 2014
Chronic allograft nephropathy (CAN) is the leading cause of late allograft loss after renal transplantation (RT), which continues to remain an unresolved problem. A rat model of CAN was first described in 1969 by White et al. Although the rat model of RT
Haylor, John, Shrestha, Badri
core   +2 more sources

Chronic allograft rejection [PDF]

open access: yesCurrent Opinion in Organ Transplantation, 2015
New developments suggest that the graft itself and molecules expressed within the graft microenvironment dictate the phenotype and evolution of chronic rejection.Once ischemia-reperfusion injury, cellular and humoral immune responses target the microvasculature, the associated local tissue hypoxia results in hypoxia-inducible factor 1α-dependent ...
Johannes, Wedel   +4 more
openaire   +2 more sources

Immunosuppressive drugs in organ transplantation to prevent allograft rejection: Mode of action and side effects

open access: yesJournal of Immunological Sciences, 2019
Organ transplantation is a life-saving therapeutic intervention that contributes to a better quality of life in patients with end-stage organ failure.
Elisa Claeys, K. Vermeire
semanticscholar   +1 more source

Alternatively Expressed Genes Identified in the CD4 T Cells of Allograft Rejection Mice

open access: yesCell Transplantation, 2011
Allograft rejection is a leading cause for the failure of allotransplantation. CD4 + T cells play critical roles in this process. The identification of genes that alternatively expressed in CD4 + T cells during allograft rejection will provide critical ...
Jia Xu   +8 more
doaj   +1 more source

Tissue typing by unidirectional mixed lymphocyte culture. 3. The relationship of in vitro lymphocyte compatibility to renal allograft rejection [PDF]

open access: yes, 1971
We applied unidirectional MLC test to renal allograft in dogs, and investigated the correlation between the growth rates of MLC reaction and the intensity of rejection of the kidney transplants or the postoperative renal function.
Tsunemitsu, Kensuke
core   +1 more source

Review: The transcripts associated with organ allograft rejection

open access: yesAmerican Journal of Transplantation, 2018
The molecular mechanisms operating in human organ transplant rejection are best inferred from the mRNAs expressed in biopsies because the corresponding proteins often have low expression and short half‐lives, while small non‐coding RNAs lack specificity.
P. Halloran   +6 more
semanticscholar   +1 more source

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