Results 41 to 50 of about 484,803 (308)

Biomarkers in solid organ transplantation: establishing personalized transplantation medicine. [PDF]

, 2011
Technological advances in molecular and in silico research have enabled significant progress towards personalized transplantation medicine. It is now possible to conduct comprehensive biomarker development studies of transplant organ pathologies ...
Khatri, Purvesh, Roedder, Silke, Sarwal, Minnie M, Vitalone, Matthew   +3 more
core   +3 more sources

GC/MS-based urine metabolomics analysis of renal allograft recipients with acute rejection

Journal of Translational Medicine, 2018
Background Acute renal allograft rejection is a common complication after renal transplantation that often leads to chronic rejection and ultimate graft loss.
Long Zheng, Jina Wang, Wenjun Gao, Chao Hu, Shuo Wang, Ruiming Rong, Yinlong Guo, Tongyu Zhu, Dong Zhu   +8 more
doaj   +1 more source

Piperlongumine alleviates corneal allograft rejection via suppressing angiogenesis and inflammation

Frontiers in Immunology, 2022
BackgroundNeovascularization and inflammatory response are two essential features of corneal allograft rejection. Here, we investigated the impact of Piperlongumine (PL) on alleviating corneal allograft rejection, primarily focusing on pathological ...
Xiangyu Fan, Jini Qiu, Tianjie Yuan, Jing Zhang, Jing Zhang, Jing Zhang, Jianjiang Xu, Jianjiang Xu, Jianjiang Xu, Jianjiang Xu   +9 more
doaj   +1 more source

Macrophage subpopulations and their impact on chronic allograft rejection versus graft acceptance in a mouse heart transplant model

American Journal of Transplantation, 2018
Macrophages infiltrating the allografts are heterogeneous, consisting of proinflammatory (M1 cells) as well as antiinflammatory and fibrogenic phenotypes (M2 cells); they affect transplantation outcomes via diverse mechanisms.
Yue Zhao, Song Chen, P. Lan, Chenglin Wu, Yaling Dou, Xiang Xiao, Zhiqiang Zhang, L. Minze, Xiaoshun He, Wenhao Chen, Xian C. Li   +10 more
semanticscholar   +1 more source

CURRENT VIEW ON MORPHOLOGY OF ACUTE REJECTION IN LIVER TRANSPLANTATION

Вестник трансплантологии и искусственных органов, 2012
We present a scientific literature data analysis of morphological features and severity criteria of the liver allograft acute rejection during last 20 years.
L.V. Shkalova, I.M. Iljinsky, O.M. Tsirulnikova   +2 more
doaj   +1 more source

Donor‐Derived Exosomes With Lung Self‐Antigens in Human Lung Allograft Rejection

American Journal of Transplantation, 2017
The immunological role of exosomes in allograft rejection remains unknown. We sought to determine whether exosomes are induced during lung allograft rejection and to define the antigenic compositions of HLA, lung‐associated self‐antigens (SAgs) and ...
M. Gunasekaran, Z. Xu, Deepak K. Nayak, Monal Sharma, R. Hachem, R. Walia, Ross M. Bremner, M. Smith, T. Mohanakumar   +8 more
semanticscholar   +1 more source

Randomized preclinical study of machine perfusion in vascularized composite allografts

BJS (British Journal of Surgery), EarlyView., 2020
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin, J. P. Stone, J. Kerr, A. Geraghty, L. Joseph, A. Montero‐Fernandez, J. K. Wong, J. E. Fildes   +7 more
wiley   +1 more source

Evaluation of liver stiffness measurement–based scores in liver transplantation recipients

Liver Transplantation, EarlyView., 2022
Abstract Combining bioclinical parameters with liver stiffness measurement (LSM) has improved the diagnostic performance of vibration‐controlled transient elastography (VCTE) for detection of advanced fibrosis in patients with chronic liver disease. However, this approach has not yet been tested in liver transplantation (LT) recipients.
Tamoore Arshad, Chandra S. Bhati, Anh T. Bui, Michael Tseng, Dylan Vainer, Austin Miller, Marie‐Claire Evans, Taseen Syed, Vaishali Patel, Michael O. Idowu, Mark Muthiah, Mohammad Shadab Siddiqui   +11 more
wiley   +1 more source

Cell-free DNA for the detection of kidney allograft rejection

Nature Medicine
Donor-derived cell-free DNA (dd-cfDNA) is an emerging noninvasive biomarker that has the potential to detect allograft injury. The capacity of dd-cfDNA to detect kidney allograft rejection and its added clinical value beyond standard of care patient ...
O. Aubert, Cindy Ursule-Dufait, Romain Brousse, Juliette Gueguen, M. Racapé, M. Raynaud, E. Van Loon, A. Pagliazzi, Edmund Huang, Stanley C Jordan, Kenneth D Chavin, Gaurav Gupta, Dhiren Kumar, T. Alhamad, Sanjiv Anand, J. Sánchez-García, B. Abdalla, Julien Hogan, R. Garro, D. Dadhania, Pranjal Jain, Didier A. Mandelbrot, M. Naesens, R. Dandamudi, V. Dharnidharka, Dany Anglicheau, C. Lefaucheur, A. Loupy   +27 more
semanticscholar   +1 more source

Role of Memory T Cells in Allograft Rejection and Tolerance

Frontiers in Immunology, 2017
Memory T cells are characterized by their low activation threshold, robust effector functions, and resistance to conventional immunosuppression and costimulation blockade.
G. Benichou, B. Gonzalez, J. Marino, K. Ayasoufi, A. Valujskikh   +4 more
semanticscholar   +1 more source