Results 181 to 190 of about 10,210 (217)
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Clinical Obstetrics and Gynecology, 1999
For the fetuses who are at risk for antenatal or postnatal sequelae from AIT, prevention and treatment are now possible. This requires the attention of the obstetrician to factors in the patient's history and early referral to a center experienced in the diagnosis and management of fetal AIT.
D W, Skupski, J B, Bussel
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For the fetuses who are at risk for antenatal or postnatal sequelae from AIT, prevention and treatment are now possible. This requires the attention of the obstetrician to factors in the patient's history and early referral to a center experienced in the diagnosis and management of fetal AIT.
D W, Skupski, J B, Bussel
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Alloimmune Neonatal Neutropenia
Journal of Pediatric Hematology/Oncology, 1991In three neonates, the diagnosis of anti-NA1 alloimmune neutropenia related to maternal immunization against fetal polymorphonuclear leukocytes (PMN) antigens was achieved by serum antibody screening and PMN phenotyping. All the children were small for date and exhibited bacterial infection within days 2-13. Neutropenia persisted until days 20-50. High-
J, Cartron +6 more
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Neonatal Alloimmune Amegakaryocytosis
Vox Sanguinis, 1988Abstract. A case of neonatal alloimmune thrombocytopenia with amegakaryocytosis is described. The baby was treated by double‐volume exchange transfusion with only a temporary benefit; 2 weeks of steroid treatment were unsuccessful but the platelet count did increase transiently after infusion of random donor platelets.
Nicola Bizzaro, Gianfranco Dianese
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Human Leukocyte Antigen Alloimmunization and Alloimmune Platelet Refractoriness
Transfusion Medicine Reviews, 2020Despite significant advancements in the production of platelet products, storage, and transfusion, transfusion refractoriness remains a significant clinical problem, affecting up to 14% of hematological patients receiving platelet transfusions. Human leukocyte antigen (HLA) alloimmunization is a major cause of immune platelet refractoriness, and its ...
Anno, Saris, Katerina, Pavenski
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Fetal Alloimmune Thrombocytopenia
Obstetrical & Gynecological Survey, 1997Alloimmune thrombocytopenia is a serious fetal disorder resulting from platelet-antigen incompatibility between the mother and fetus. The diagnosis is usually made after the discovery of unexpected neonatal thrombocytopenia. Approximately 10 to 20 percent of affected fetuses have intracranial hemorrhages, one quarter to one half of which occur in utero.
J B, Bussel +3 more
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Neonatal alloimmune thrombocytopenia
Blood Reviews, 1989Neonatal alloimmune thrombocytopenia (NAIT) occurs when maternal alloantibodies to antigens present on fetal platelets cause their immune destruction resulting in thrombocytopenia in the newborn infant or fetus. Bleeding may be severe; intracranial haemorrhage and permanent neurological damage are the most serious complications. Despite the severity of
P O, Skacel, M, Contreras
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Journal of Pediatric Hematology/Oncology, 2003
Alloimmunization against platelet antigens may take place during pregnancy and following transfusion or transplantation. The resulting antibodies bind to the target platelet antigens and may lead to a rapid sequestration of incompatible platelets.
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Alloimmunization against platelet antigens may take place during pregnancy and following transfusion or transplantation. The resulting antibodies bind to the target platelet antigens and may lead to a rapid sequestration of incompatible platelets.
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Neonatal Alloimmune Thrombocytopenia
Transfusion Medicine Reviews, 1994EONATAL alloimmune thrombocytopenia (NAIT) is a relatively rare disease, occurring in 1 in 3,000 to l in 5,000 births. 1.2 The platelet equivalent of hemolytic disease of the newbom, NAIT is the result of matemai alloimmunization against a platelet antigen present on fetal and pa ternal platelets but absent on matemai platelets.
M, Goldman +4 more
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Fetomaternal alloimmune thrombocytopenia
Transfusion and Apheresis Science, 2001Thrombocytopenia is the second commonest haematological abnormality in the neonatal period after anaemia due to iatrogenic blood letting. One to four percent of all newborn babies have a platelet count < 150 x 10(9)/l at birth and approximately 20-40% of neonates in intensive care units are affected by neonatal thrombocytopenia.
R, Ahya, M L, Turner, S J, Urbaniak
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Vox Sanguinis, 1993
The Winnipeg Rh Laboratory has reviewed its experiences with maternal CW alloimmunization. From September 24, 1956, to March 31, 1992, 12 women with significant CW alloimmunization underwent 18 pregnancies. In 3 (4 pregnancies) the antibody, despite its strength, was 'naturally occurring' (i.e. there was no known exposure to CW-positive red cells). The
J M, Bowman, J, Pollock
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The Winnipeg Rh Laboratory has reviewed its experiences with maternal CW alloimmunization. From September 24, 1956, to March 31, 1992, 12 women with significant CW alloimmunization underwent 18 pregnancies. In 3 (4 pregnancies) the antibody, despite its strength, was 'naturally occurring' (i.e. there was no known exposure to CW-positive red cells). The
J M, Bowman, J, Pollock
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