Results 181 to 190 of about 14,033 (212)

Platelet transfusion refractoriness due to HLA alloimmunization: Evolving paradigms in mechanisms and management

Blood Reviews, 2023
Platelet transfusion refractoriness due HLA alloimmunization presents a significant medical problem, particularly among multiply transfused patients with hematologic malignancies and those undergoing hematopoietic stem cell transplants.
Ralph R Vassallo
exaly   +2 more sources

Human Leukocyte Antigen Alloimmunization and Alloimmune Platelet Refractoriness.

Transfusion Medicine Reviews, 2020
Despite significant advancements in the production of platelet products, storage, and transfusion, transfusion refractoriness remains a significant clinical problem, affecting up to 14% of hematological patients receiving platelet transfusions.
A. Saris, K. Pavenski
semanticscholar   +2 more sources

Rate of D‐alloimmunization in trauma does not depend on the number of RhD‐positive units transfused: The BEST collaborative study

Transfusion, 2022
Evidence indicates the life‐saving benefits of early blood product transfusion in severe trauma resuscitation. Many of these products will be RhD‐positive, so understanding the D‐alloimmunization rate is important.
J. Seheult, J. Callum, M. Delaney, Rosanna Drake, N. Dunbar, S. Harm, J. R. Hess, Bryon P Jackson, A. Javanbakht, S. Moore, Melissa S. Murphy, J. Raval, J. Staves, Erin E Tuott, S. Wendel, A. Ziman, M. Yazer   +16 more
semanticscholar   +1 more source

Erythropoietic suppression in fetal anemia because of Kell alloimmunization

American Journal of Obstetrics and Gynecology, 1994
OBJECTIVE: Our purpose was to test the hypothesis that maternal anti-Kell alloimmunization produces fetal anemia by erythroid ...
Nicholas M Fisk, Umberto Nicolini, Charles H Rodeck   +2 more
exaly   +2 more sources

Anti‐D alloimmunization in Rh(D) negative adults with severe traumatic injury

Transfusion, 2021
Widely varying rates of alloimmunization associated with transfusing uncrossmatched RBC products to trauma patients as part of hemostatic resuscitation have been reported.
J. Raval, Kathleen M. Madden, M. Neal, S. Moore   +3 more
semanticscholar   +1 more source

Rate of RhD‐alloimmunization after the transfusion of multiple RhD‐positive primary red blood cell‐containing products

Transfusion, 2021
Early transfusion reduces mortality in bleeding patients. In this setting, RhD‐positive blood products might be transfused. This study determined the association between the RhD‐alloimmunization rate and the number of RhD‐positive products transfused.
Mark H. Yazer, D. Triulzi, J. Sperry, J. Seheult   +3 more
semanticscholar   +1 more source

Guideline No. 448: Prevention of Rh D Alloimmunization.

Journal of Obstetrics and Gynaecology Canada
OBJECTIVE This guideline provides recommendations for the prevention of Rh D alloimmunization (isoimmunization) in pregnancy, including parental testing, routine postpartum and antepartum prophylaxis, and other clinical indications for prophylaxis ...
Karen Fung-Kee-Fung, Karen Wong, Jennifer Walsh, Candyce Hamel, Gwen Clarke   +4 more
semanticscholar   +1 more source

Multidisciplinary management of anti‐PP1Pk or anti‐P alloimmunization during pregnancy: A new case with anti‐P and a literature review

Transfusion, 2021
Red blood cell alloimmunization is the first cause of fetal and neonatal anemia. Alloimmunizations with anti‐PP1Pk or anti‐P can cause recurrent miscarriages and hemolytic disease of the fetus and newborn in the 2nd and 3rd trimesters of pregnancy.
Marlène Sohier Lépine, V. Goua, O. Debouverie, C. Giraud, C. Rafat, V. Thonier, Badrdine El Masmouhi, C. T. N'dour, S. Huguet-Jacquot, A. Mailloux, A. Cortey, J. Jouannic, E. Maisonneuve   +12 more
semanticscholar   +1 more source

Neonatal and Obstetrical Outcomes of Pregnancies Complicated by Alloimmunization.

Pediatrics
BACKGROUND AND OBJECTIVES Despite advances in the prevention of rhesus (Rh)(D) alloimmunization, alloantibodies to Rh(D) and non-Rh(D) red blood cell antigens continue to be detected in ∼4% of US pregnancies and can result in hemolytic disease of the ...
T. Bahr, Sarah M. Tweddell, Jennifer M. Zalla, Donna Dizon-Townson, R. Ohls, Erick Henry, S. Ilstrup, W. Kelley, Con Yee Ling, Peter C Lindgren, E. O’Brien, Robert D. Christensen   +11 more
semanticscholar   +1 more source