Results 171 to 180 of about 48,909 (251)
Boreas, EarlyView.Palaeoenvironmental records along the eastern coast of Thailand remain sparse, with only a few studies attempting to reconstruct past climatic and environmental conditions. However, additional palaeoenvironmental, palaeoclimatic and sea‐level records are needed to improve our understanding of coastal evolution and local environmental changes.
Sakonvan Chawchai +7 more
wiley +1 more source
Boreas, EarlyView.Bears deviate from the inhibitory cascade model (ICM) during molar size evolution, with two significant deviations linked to changes in diet: Ursus minimus and Ursus deningeri. Many bears exhibit a ‘partial ICM’, highlighting the relationship between relative molar size, dietary adaptations and dental development across different species.
Anneke H. van Heteren, A. Stefanie Luft
wiley +1 more source
Brain Pathology, EarlyView.The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown +7 more
wiley +1 more source
Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
British Journal of Pharmacology, EarlyView.Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander +5 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller +3 more
wiley +1 more source
Homo luzonensis and the role of homoplasy in the morphology of hominin insular species
Cladistics, EarlyView.Abstract Homo luzonensis lived during the upper Pleistocene in the northern Philippines, east of the Wallace line. The few specimens attributed to this species show a mosaic of plesiomorphies for the genus Homo and apomorphies found in upper Pleistocene Homo species.
Pierre Gousset +4 more
wiley +1 more source
Cell Proliferation, EarlyView.Schematic summarizing the pathway of sSema4D from γδ T cells inhibiting osteoblast differentiation in BRONJ. ABSTRACT Bisphosphonate‐related osteonecrosis of the jaw (BRONJ) is a severe complication in patients undergoing long‐term bisphosphonate therapy, while our knowledge on the pathogenesis of BRONJ is far from sufficient.
Lingling Ou +15 more
wiley +1 more source
Publisher Correction: Intraskeletal histovariability, allometric growth patterns, and their functional implications in bird-like dinosaurs. [PDF]
Sci Rep, 2018 Prondvai E +3 more
europepmc +1 more source
Automating Ecological and Fisheries Modelling With Agentic AI
Fish and Fisheries, EarlyView.ABSTRACT Fisheries modelling requires specialist training, but the availability of suitably skilled modellers is limiting delivery of science to inform management. Agentic AI can automate computing workflows and will increasingly be used in ecological modelling.
Christopher J. Brown +3 more
wiley +1 more source