Results 161 to 170 of about 14,888 (262)

Allometric models and aboveground biomass stocks of a West African Sudan Savannah watershed in Benin. [PDF]

Carbon Balance Manag, 2016
Chabi A, Lautenbach S, Orekan VO, Kyei-Baffour N.   +3 more
europepmc   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Human Pharmacokinetic Prediction of Antibody-Drug Conjugates Using Human FcRn Transgenic Mice. [PDF]

Clin Transl Sci
Nakagawa K, Haraya K.
europepmc   +1 more source

Mirikizumab pharmacokinetics and exposure–response in pediatric patients with moderate‐to‐severe ulcerative colitis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 474-485, March 2025.
Abstract Mirikizumab is a p19‐directed anti‐interleukin‐23 antibody approved for the treatment of adults with moderate‐to‐severe ulcerative colitis (UC). Here, we report the first data of mirikizumab pharmacokinetics (PK) and exposure–response (E/R) relationships in pediatric participants (aged 2 to <18 years weighing >10 kg) with moderate‐to‐severe UC
Yuki Otani, Laiyi Chua, Wendy J. Komocsar, Amy Larkin, Jordan Johns, Xin Zhang   +5 more
wiley   +1 more source

Pharmacokinetic Model Based Sensitivity Analysis to Lower Recruitment Burden for Young Children Requiring Intravenous Immunoglobulin G Replacement. [PDF]

CPT Pharmacometrics Syst Pharmacol
Dumas T, Mehr S, Avila R, Doman A, Kestenberg K, Melamed I.   +5 more
europepmc   +1 more source

Chaetocin Induces Ferroptosis in Cisplatin‐Resistant Ovarian Cancer Cells Through Neddylation‐Mediated TFRC Upregulation

Phytotherapy Research, EarlyView.
Chaetocin induces ferroptosis in cisplatin‐resistant ovarian cancer cells through neddylation‐mediated TFRC upregulation. ABSTRACT Ovarian cancer (OV) is a highly lethal gynecological tumor, often developing platinum chemotherapy resistance and treatment failure.
Hanfei Xie, Wumin Dai, Lu Sun, Wangang Gong, Tao Zhu, Yingli Zhang   +5 more
wiley   +1 more source

Physiologically based pharmacokinetic modeling to predict human pharmacokinetics of a novel mithramycin analog for Ewing sarcoma. [PDF]

Cancer Chemother Pharmacol
Niloy KK, Horn J, Bhuiyan NH, Bhosale SS, Shaaban KA, Prisinzano TE, Thorson JS, Rohr J, Leggas M.   +8 more
europepmc   +1 more source

Allometric modeling for biomass estimation in remote sensing

Allometric modeling for biomass estimation in remote sensing
[ABSTRACT]This research develops an allometric model for estimation of biomass based on the height and DBH of trees in the forests of Iran. Without an accurate allometric model, we can’t estimate true biomass from SAR images. After extensive field investigations, 124 trees are selected from the 4 different dominant tree species for the development of ...
openaire   +1 more source

Hinokitiol Promotes Neural Repair After Spinal Cord Injury by Reprogramming Microglial Inflammatory and Redox Responses

Phytotherapy Research, EarlyView.
Schematic illustration showing that Hinokitiol promotes neural repair after spinal cord injury by activating the Keap1/Nrf2/HO‐1 signaling pathway and reprogramming microglial inflammatory‐redox responses. ABSTRACT Secondary neuroinflammation and oxidative stress, driven partly by maladaptive microglial activation, limit recovery after spinal cord ...
Wenhao Zhang, Jing Wang, Tianyi Wang, Qihao Fu, Jiawen Xu, Chaochen Li, Zheng Zhou, Chenxi Zhang, Guanhua Xu, Mingjie Xia, Zhiming Cui   +10 more
wiley   +1 more source

Associations Between Teenage Motherhood, Perinatal Cortical Maturation, and Risk of Psychopathology in Children: The Mediating Role of Pregnancy Complications. [PDF]

Biol Psychiatry Glob Open Sci
Paysserand A, Belzeaux R, Auzias G, Lefrere A, Cachia A, Deruelle P, Pizzagalli F, Deruelle C.   +7 more
europepmc   +1 more source