Results 51 to 60 of about 45,108 (330)

Retrospective and Prospective Human Intravenous and Oral Pharmacokinetic Projection of Dipeptidyl peptidase-IV Inhibitors Using Simple Allometric Principles – Case Studies of ABT-279, ABT-341, Alogliptin, Carmegliptin, Sitagliptin and Vildagliptin

Journal of Pharmacy & Pharmaceutical Sciences, 2015
Purpose: The purpose of this exercise was to explore the utility of allometric scaling approach for the prediction of intravenous and oral pharmacokinetics of six dipeptidy peptidase-IV (DPP-IV) inhibitors viz. ABT-279, ABT-341, alogliptin, carmegliptin,
Ravindranath R Gilibili, Ravi Kanth Bhamidipati, Ramesh Mullangi, Nuggehally R Srinivas   +3 more
doaj   +1 more source

Allometry and morphological trait relationship in the sexually dimorphic Chinese dobsonfly, Acanthacorydalis asiatica (Wood-Mason, 1884) (Megaloptera, Corydalidae) [PDF]

ZooKeys, 2019
Male insects with large weapons such as horns and elongate mandibles would be expected to invest more on such structures than other parts of the body for advantages in male to male competition for mating.
Chengquan Cao, Pei Yu, Fumio Hayashi
doaj   +3 more sources

Allometry and sexual dimorphism of the Neotropical freshwater anomuran Aegla marginata Bond-Buckup & Buckup, 1994 (Crustacea, Anomura, Aeglidae)

Nauplius
This study analyzes ontogenetic allometry in Aegla marginata Bond-Buckup & Buckup, 1994, a freshwater crustacean, in order to evaluate the growth pattern and the presence of sexual dimorphism, using a multivariate approach.
Alexandre Ribeiro da Silva, Gabriel de Paula Paciencia, Pitágoras Conceição Bispo, Antonio Leão Castilho   +3 more
doaj   +1 more source

Allometry of brain metabolism [PDF]

Proceedings of the National Academy of Sciences, 2013
Allometry refers to biological scaling relationships (1). With regard to metabolic rate, the earliest allometric studies demonstrated a complex inverse relationship between body size and resting metabolic rate (2⇓–4). Subsequent studies have focused, without much success, on describing the cellular mechanisms of this relationship.
openaire   +2 more sources

Sensory adaptations reshaped intrinsic factors underlying morphological diversification in bats

BMC Biology, 2021
Background Morphological evolution may be impacted by both intrinsic (developmental, constructional, physiological) and extrinsic (ecological opportunity and release) factors, but can intrinsic factors be altered by adaptive evolution and, if so, do they
J. H. Arbour, A. A. Curtis, S. E. Santana   +2 more
doaj   +1 more source

Using the root spread information of pioneer plants to quantify their mitigation potential against shallow landslides and erosion in temperate humid climates [PDF]

, 2016
The aim of this paper was to quantify the mitigation potential of pioneer herbs against shallow landslidesand erosion in temperate humid climates and to identify key plant information to aid species selectionfor slope stabilisation. The objectives ranged
Gonzalez-Ollauri, Alejandro, Mickovski, Slobodan B.   +1 more
core   +1 more source

Male mate choice scales female ornament allometry in a cichlid fish

BMC Evolutionary Biology, 2010
Background Studies addressing the adaptive significance of female ornamentation have gained ground recently. However, the expression of female ornaments in relation to body size, known as trait allometry, still remains unexplored.
Kullmann Harald, Herder Fabian, Bakker Theo CM, Baldauf Sebastian A, Thünken Timo   +4 more
doaj   +1 more source

A Statistical Mechanics Model to Decode Tissue Crosstalk During Graft Formation

Advanced Science, EarlyView.
We introduce a statistical mechanics framework to decode the genomic crosstalk governing plant grafting. By integrating evolutionary game theory with transcriptomics, we reconstruct idopNetworks (informative, dynamic, omnidirectional, and personalized networks) that map scion–rootstock interactions.
Ang Dong, Yihan Meng, Stephen Shing‐Toung Yau, Shing‐Tung Yau, Rongling Wu   +4 more
wiley   +1 more source

Phylogenomics reveals the evolution of floral traits associated with pollinators and pollinator–prey conflict within the carnivorous Pinguicula subgenus Temnoceras

American Journal of Botany, EarlyView.
Abstract Premise The carnivorous plant genus Pinguicula (Lentibulariaceae) exhibits remarkable floral diversity associated with pollination, particularly in the largest subgenus Temnoceras, which spans Mexico and Central America. Despite this diversity, the relationships between species and the evolution of key floral traits remain unresolved. Here, we
Yunjia Liu, Qianshi Lin, Steven J. Fleck, Martín Mata‐Rosas, Enrique Ibarra‐Laclette, Tanya Renner   +5 more
wiley   +1 more source

Quantitative assessment of masticatory muscles based on skull muscle attachment areas in Carnivora

The Anatomical Record, EarlyView.
Abstract Masticatory muscles are composed of the temporalis, masseter, and pterygoid muscles in mammals. Each muscle has a different origin on the skull and insertion on the mandible; thus, all masticatory muscles contract in different directions. Collecting in vivo data and directly measuring the masticatory muscles anatomically in various Carnivora ...
Kai Ito, Mugino O. Kubo, Ryo Kodera, Sei‐ichiro Takeda, Hideki Endo   +4 more
wiley   +1 more source