Results 71 to 80 of about 17,318 (170)

Exploring Disulfide Bridge as a Tool to Improve Pioglitazone’s Neuroprotective Potential: Toward the Development of Prolonged‐Acting MAO‐B/PPARγ Modulators

open access: yesChemMedChem, Volume 21, Issue 15, 14 August 2026.
Pioglitazone is an antidiabetic drug acting as a peroxisome proliferator‐activated receptor γ (PPARγ) agonist and later repositioned as a monoamine oxidase B (MAO‐B) inhibitor. Despite promising preclinical premises, it showed a lack of efficacy in clinical trials as a treatment for neurodegenerative diseases.
Filippo Basagni   +12 more
wiley   +1 more source

A roadmap to key traits of invasive Drosophilidae

open access: yesBiological Reviews, Volume 101, Issue 4, Page 1805-1829, August 2026.
ABSTRACT Biological invasions have intensified in recent decades, mostly driven by international trade and travel, raising significant concerns, particularly regarding insect pests. Once non‐native species establish, they can disrupt natural ecosystem stability, undermine agroecosystem sustainability and cause substantial economic losses.
Gwenaëlle Deconninck   +14 more
wiley   +1 more source

Family History of Chronic Pain: What Impact Does It Have on Current Clinical Status? Results From an Italian Study

open access: yesEuropean Journal of Pain, Volume 30, Issue 7, August 2026.
ABSTRACT Background Although a key factor in understanding intergenerational transmission, family history of chronic pain deserves greater attention, particularly about its role as a potential mediating factor on current psychophysical status, together with other underestimated parameters (e.g., psychiatric comorbidity).
Simona Pupo   +5 more
wiley   +1 more source

On the need for biocultural approaches to restoration

open access: yesPeople and Nature, Volume 8, Issue 8, Page 2598-2609, August 2026.
Abstract Ecological restoration is gaining global momentum for climate mitigation, yet its prevailing approach, often rooted in Western technical science, frequently appears neutral while inadvertently reinforcing power imbalances and sidelining local knowledge.
Felipe Melo   +13 more
wiley   +1 more source

Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death

open access: yesPhytotherapy Research, Volume 40, Issue 8, Page 5119-5131, August 2026.
ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi   +6 more
wiley   +1 more source

What Is Your Diagnosis? Multiple Subcutaneous Lumps in a Horse

open access: yes
Veterinary Clinical Pathology, EarlyView.
Federica Meistro   +4 more
wiley   +1 more source

Impacts of a Sweet Orange Essential Oil–Based Biopesticide on Exorista larvarum, a Parasitoid Tachinid Fly With a Dual Role

open access: yesEntomologia Experimentalis et Applicata, Volume 174, Issue 8, Page 933-941, August 2026.
Lethal (mortality) and sublethal (fecundity, fertility) effects of the biopesticide Prev‐Am Plus (containing ~6% sweet orange essential oil) were assessed on the tachinid fly Exorista larvarum. Mated females were exposed via contact and oral routes across five concentrations (0.25%–20%) using protocols adapted from Apis mellifera.
Santolo Francati   +3 more
wiley   +1 more source

Comparison between liquid and tablet formulations in the treatment of congenital hypothyroidism. [PDF]

open access: yesEndocrine
Parzianello A   +7 more
europepmc   +1 more source

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