Energy-Screened Many-Body Expansion for Protein-Ligand Interactions: Examining Convergence for Metalloenzymes Through Seven-Body Interactions. [PDF]
Bowling PE, Broderick DR, Herbert JM.
europepmc +1 more source
Enhanced Endoscopic Internal Drainage of Gastric Abscess Through Additively Manufactured Stents
Postoperative gastric leaks are often treated with off‐label biliary double‐pigtail stents, yet conventional extruded designs are not optimized for leak anatomy, can migrate, and may limit abscess evacuation. PETALS is introduced to optimize transmural drainage geometry and enable patient‐specific 3D‐printable stents.
Parima Phowarasoontorn +14 more
wiley +1 more source
A second-order dynamical system for solving inverse quasi-variational inequalities and its application. [PDF]
Gan T, Khan VK, Ahmad MK, Cai QB.
europepmc +1 more source
Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec +5 more
wiley +1 more source
Existence of variational solutions to doubly nonlinear systems in nondecreasing domains. [PDF]
Schätzler L +3 more
europepmc +1 more source
Microengineered Gradient Hydrogels for Mechanobiology
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong +4 more
wiley +1 more source
A hybrid fuzzy-PIDD² control strategy for coordinated LFC and AVR in renewable-integrated multi-area power systems. [PDF]
Omar MHT, Hamdy RA, Kotb H.
europepmc +1 more source
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter +5 more
wiley +1 more source
qsGW quasiparticle and GW-BSE excitation energies of 133,885 molecules. [PDF]
Baum D, Förster A, Visscher L.
europepmc +1 more source

