Results 61 to 70 of about 104,376 (236)

Six Permutation Patterns Force Quasirandomness

Discrete Analysis
Six permutation patterns force quasirandomness, Discrete Analysis 2024:8, 26 pp. Quasirandomness is a major theme in combinatorics, with several important applications.
Gabriel Crudele, Peter Dukes, Jonathan A. Noel   +2 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Fixed point results for almost (? - ?? )-contractions on quasi metric spaces and an application

This research paper investigated fixed point results for almost (zeta - theta rho)-contractions in the context of quasi-metric spaces. The study focused on a specific class of (zeta - theta rho)-contractions, which exhibit a more relaxed form of ...
Gungor, Gonca Durmaz, Altun, Ishak
core   +1 more source

Types of almost continuity

, 1983
The differences for properties of the range space f ( X ) f(X) are considered for functions f : X → Y f:X \to Y , where f f is almost ...
B. D. Garrett, K. R. Kellum
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Almost Fixed Point Property of Nonexpansive Mappings

, 2007
Introduction Recently Kijima [2] and Shimizu and Takahashi [5] proved some fixed point theorems for singlevalued and multivalued mappings respectively in a metric space with some kind of convexity. The purpose of this note is to extend these results to a
S. N. Mishra, Pp In Gs
core  

Exceptional times when the KPZ fixed point violates Johansson's conjecture on maximizer uniqueness

, 2022
In 2002, Johansson conjectured that the maximum of the Airy$_2$ process minus the parabola $x^2$ is almost surely achieved at a unique location. This result was proved a decade later by Corwin and Hammond; Moreno Flores, Quastel and Remenik; and Pimentel.
Hegde, Milind, Matetski, Konstantin, Hammond, Alan, Corwin, Ivan   +3 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

A fixed point theorem for Lie groups acting on buildings and applications to Kac-Moody theory

, 2012
We establish a fixed point property for a certain class of locally compact groups, including almost connected Lie groups and compact groups of finite abelian width, which act by simplicial isometries on finite rank buildings with measurable stabilisers ...
Marquis, Timothée, Timothee Marquis
core   +1 more source