Results 171 to 180 of about 415,002 (218)

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source

Aperiodicity in Low Dimensions. [PDF]

Materials (Basel)
Avramov PV, Tian H, Li L.
europepmc   +1 more source

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

Advanced Science, EarlyView.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park, Zahra Rezaei, Nam Ho Bae, Donggee Rho, Da‐Seul Kim, EunYoung Go, YoungTae Seo, Seok Jae Lee, Won Chan Seo, Luke P. Lee, HeaYeon Lee, Su Ryon Shin   +11 more
wiley   +1 more source

Enhancement of inter-/intra-reader agreement using the Prostate Imaging Reporting and Data System version 2.1 for prostate cancer detection in magnetic resonance imaging/transrectal ultrasound software fusion prostate biopsy. [PDF]

Investig Clin Urol
Song WH, Kim TU, Ryu HS, Yun MS, Park SW.   +4 more
europepmc   +1 more source

Mechanism of Solid Solution‐Driven Texture Induced by Ag Doping in YBCO Superconductor

Advanced Science, EarlyView.
Ag‐doped YBCO with a designed concentration gradient is produced by dual‐material co‐extrusion and freeze‐drying. During annealing, Ag+ ions diffuse into Y123, substituting for Cu(1) and inducing c‐axis relaxation. This leads to the formation of [001]‐oriented YBCAO, creating a coherent interface that templates the textured growth of Y123. Consequently,
Fenyan Zhao, Baoqiang Zhang, Xiyang Su, Yantang Zhao, Xingyi Zhang   +4 more
wiley   +1 more source

High‐Order Nonlinear Photonic Crystal with Ordered Structures for Giant Enhancement of Frequency Tripling

Advanced Science, EarlyView.
A meta‐YAG crystal with artificially order/disorder structures was fabricated to realize the efficient third‐harmonic generation at 343 nm with a conversion efficiency of 4.5×10−3, surpassing six orders of magnitude compared to bulk YAG crystal. Moreover, a wide spectral tunability from 331 to 356 nm was also achieved in the meta‐YAG, indicating its ...
Xiaotian Guo, Qiaoling Han, Fei Liang, Bin Zhang, Dazhi Lu, Haohai Yu, Huaijin Zhang   +6 more
wiley   +1 more source

Ultrabroadband, achromatic, and non-diffracting perfect optical vortex generation via radial momentum control in dielectric metasurfaces. [PDF]

Nat Commun
Xia T, Xie Z, Zhang Q, Xiao W, Yang H, Hu Y, Duan H, Cai Y, Yuan X.   +8 more
europepmc   +1 more source

Synergistic Spin‐Polarization and Single‐Atom Engineering in Magnetic Heterojunctions for Efficient Solar Water Splitting

Advanced Science, EarlyView.
High‐throughput screening led to the identification of 67 Z‐scheme heterojunctions (comprising 2D magnetic transition metal halides and non‐magnetic transition metal chalcogenides). For CrI3/MoTe2 and CrI3/WTe2, electronic structure analysis demonstrated that synergistic crystallographic point group and built‐in electric field effects generate a ...
Hongyang Ren, Zhenzhou Guo, Huirong Wu, Peilin Huang, Jie Yang, Jie Zhang, Guangqian Ding, Hongkuan Yuan, Biao Wang   +8 more
wiley   +1 more source

Brillouin-induced Kerr frequency comb in normal dispersion fiber Fabry Perot resonators. [PDF]

Nat Commun
Bunel T, Lumeau J, Moreau A, Fernandez A, Llopis O, Bourcier G, Perego AM, Conforti M, Mussot A.   +8 more
europepmc   +1 more source