Results 171 to 180 of about 98,818 (275)

PAIR: Reconstructing Single‐Cell Open‐Chromatin Landscapes for Transcription Factor Regulome Mapping

Advanced Science, EarlyView.
scATAC‐seq analysis is often constrained by limited sequencing depth, extreme sparsity, and pervasive technical missingness. PAIR is a probabilistic framework that restores scATAC‐seq accessibility profiles by directly modeling the native cell–peak bipartite structure of chromatin accessibility.
Yanchi Su, Qi Qi, Yi Fan, Yubo Wang, Gaoyang Hao, Ka‐Chun Wong, Yunhe Wang, Xiangtao Li   +7 more
wiley   +1 more source

Remodeling of homoeolog expression bias buffers stress response in allotetraploid cotton. [PDF]

BMC Plant Biol
Cao J, Sun R, Deng T, Yu H, Chen J, Zhao Y, Yu D, Sun Y.   +7 more
europepmc   +1 more source

Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices

Advanced Science, EarlyView.
Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen, Wei Zeng, Zherui Zhao, JiYu Zhao, Ziyan Huang, Zhuo Chen, Kui Zhou, Guanglong Ding, Su‐Ting Han, Ye Zhou   +9 more
wiley   +1 more source

GWKBR: a novel method integrating machine learning and Bayesian inference framework to improve genomic prediction accuracy. [PDF]

Brief Bioinform
Wang X, Jiang J, Zhang Z, Zhang Y.
europepmc   +1 more source

Tri‐Layer Solid‐State Nanopore Arrays with Crosstalk Suppression for High‐Throughput, Femtomolar‐Level Biosensing

Advanced Science, EarlyView.
The critical pore spacing—approximately twenty times the pore radius—required to minimize electric field coupling is determined via finite element analysis. A multi‐layered Al2O3/Au/Si3N4 nanopore structure fabricated by helium ion beam lithography is proposed, enabling quantitative analysis of the target analyte while mitigating inter‐pore crosstalk ...
Silu Feng, Qinglong Luo, Siqi Ai, Suiwei Shen, Chengyong Wang, Zhishan Yuan   +5 more
wiley   +1 more source

Optoelectronic‐Driven van der Waals Ferroelectric Materials‐Based Memory Devices for Retinomorphic and In‐Sensory Hardware

Advanced Science, EarlyView.
2D ferroelectrics materials enabling non‐volatile polarization memory, optical excitability, and neuromorphic processing within a unified material and provides a mechanistic analysis of polarization‐induced band modulation, including photon‐assisted domain reorientation, switching kinetics, and interfacial dipole coupling that governs resistive ...
Parthasarathi Pal, Yeong‐Her Wang, Sanjay Kumar, Themis Prodromakis   +3 more
wiley   +1 more source

Kinetic Traps in RNA Folding: Targeted Design of Frameshifting Element Mutants by Thermodynamic and Kinetic Analysis of the Chikungunya Virus. [PDF]

J Phys Chem B
Lee S, Schlick T.
europepmc   +1 more source

Decoding Structure‐Property Relationships in Anion Exchange Membranes via a Chemically Informed Dual‐Channel Graph Attention Network

Advanced Science, EarlyView.
SPARK decodes structure‐property relationships in anion exchange membranes (AEMs) via a chemically informed dual‐channel graph attention network (DEGAT) that explicitly captures microphase separation. It outputs five‐level grades for hydroxide conductivity and alkaline stability and highlights relevant key structural units, enabling robust pre ...
Wanting Chen, Ye Hu, Zijun Xiao, Deming Xia, Bo Pang, Xuemei Wu, Gaohong He   +6 more
wiley   +1 more source

Particle partitioning and geography drive divergent microbial assembly and network connectivity in coastal South China Sea. [PDF]

Front Microbiol
Pang S, Chen S, Lin Z, Xie W, Xu Y, Zhang C.   +5 more
europepmc   +1 more source

Investigating Phase Separation in Genome Folding via Multiscale Computational Modeling

Advanced Science, EarlyView.
Phase separation is emerging as a multiscale organizing principle of genome folding across scales, from nucleosomes and transcriptional condensates to chromatin domains and nuclear compartments. By integrating physics‐based simulations with data‐driven inference, computational modeling now links molecular interactions to nuclear architecture and points
Jiahu Tang, Cibo Feng, Haibin Su, Xiakun Chu   +3 more
wiley   +1 more source