Results 171 to 180 of about 33,995 (286)

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz   +9 more
wiley   +1 more source

Uniform Bahadur Representation for LocalPolynomial Estimates of M-Regressionand Its Application to The Additive Model [PDF]

open access: yes
We use local polynomial fitting to estimate the nonparametric M-regression function for strongly mixing stationary processes {(Y_i,?X_i ) } . We establish a strong uniform consistency rate for the Bahadur representation of estimators of the regression ...
Yingcun Xia, Oliver Linton, Efang Kong
core  

Nanoplatforms for Sentinel and Tumor‐Draining Lymph Node Mapping: From Visualization to Pathway‐Informed Staging

open access: yesAdvanced Healthcare Materials, EarlyView.
Lymphotropic nanoplatforms integrate multimodal imaging with therapeutic guidance to map sentinel and tumor‐draining lymph nodes, revealing functional drainage, metastatic involvement, and nodal accessibility, while providing mechanistic insight to support precision surgical and therapeutic interventions.
Xu Chen   +7 more
wiley   +1 more source

An almost fourth order uniformly convergent scheme for reaction-diffusion problems on a piecewise uniform grid

open access: yesЧебышевский сборник, 2011
For the problem: −Ɛy ′′(x)+p(x)y(x) = f(x); x ∈ D; y(0) = α 0; y(1) = α 1the spline difference schemes on a piecewise mesh having the second order of uniform convergence are given. Also, in this paper is presented a construction of an uniformly convergent scheme with an almost fourth order of uniform convergence on a Shishkin mesh.
openaire   +1 more source

A Novel Perfused Full‐Thickness Human Skin Microphysiological System for Modeling Injury, Regeneration, Tumor Pathophysiology, and Therapeutics Development

open access: yesAdvanced Healthcare Materials, EarlyView.
What if human skin could remain fully alive and functional outside the body for weeks? A New Alternative Method (NAM) based on a vascularized full‐thickness skin microphysiological system achieves precisely this, preserving native vasculature, resident immunity, and metabolic activity for up to three weeks, while faithfully recapitulating radiation ...
Yusuf Surucu   +13 more
wiley   +1 more source

Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells

open access: yesAdvanced Materials, EarlyView.
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno   +16 more
wiley   +1 more source

Uniform convergence of nonparametric regressions in competing risk models with right censoring [PDF]

open access: yes
We consider, in the presence of covariates, non-independent competing risks that are subject to right censoring. We define a nonparametric estimator of the incident regression function through the generalized product-limit estimator of the conditional ...
Bordes, Laurent, Gneyou, Kossi Essona
core  

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