Results 191 to 200 of about 3,244,508 (257)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

An epilepsy-associated KV3.1 potassium channel variant acts via dominant-positive effect. [PDF]

J Gen Physiol
Clatot J, Monnerie H, Panzer A, Platzer K, Goldberg EM.   +4 more
europepmc   +1 more source

Digital technologies in care for older adults living alone: a scoping review. [PDF]

Innov Aging
Xu W, Yang B, Teerawichitchainan B.
europepmc   +1 more source

A Systematic Review on the Role of Postoperative Radiotherapy in Pelvic Ewing Sarcoma. [PDF]

Cancer Med
Hong A, Lim T, Lo H, Bhadri VA, Connor J, Grimison P, Lazarakis S, Lewin J, Mar J, Nicholls W, Orme L, Phillips MB, Thompson SR, Ward I, Winstanley M, Cayrol J, Omer N.   +16 more
europepmc   +1 more source

CDK4/6 inhibitors rechallenge post-progression in HR-positive HER2-negative advanced/metastatic breast cancer patients: a meta-analysis of Kaplan-Meier-reconstructed individual-level data. [PDF]

Breast Cancer Res
Veta Darkovski J, Michelon I, Gazzoni G, Mamede I, Jeong Y, Cavalcante L.   +5 more
europepmc   +1 more source

Systemic sclerosis and primary biliary cholangitis: a systematic review of case-control studies comparing isolated and overlapping disease phenotypes. [PDF]

J Scleroderma Relat Disord
Nursoy M, Mehmetoglu E, Syal A, Pasula R, Parperis K, Choudhary C, Derk CT.   +6 more
europepmc   +1 more source