Results 91 to 100 of about 10,854 (230)

Borna disease outbreak with high mortality in an alpaca herd in a previously unreported endemic area in Germany.

Transboundary and Emerging Diseases, 2020
Borna disease virus 1 (BoDV-1) is the causative agent of Borna disease, an often fatal neurologic condition of domestic mammals, including New World camelids, in endemic areas in Central Europe.
Vanessa Schulze, R. Große, J. Fürstenau, Leonie F. Forth, Arnt Ebinger, M. Richter, D. Tappe, Tanja Mertsch, K. Klose, Kore Schlottau, B. Hoffmann, D. Höper, L. Mundhenk, R. Ulrich, M. Beer, K. Müller, D. Rubbenstroth   +16 more
semanticscholar   +1 more source

Artificial Intelligence Resources for the Screening of Titles and Abstracts in Systematic Reviews: A Scoping Review

Cochrane Evidence Synthesis and Methods, Volume 4, Issue 5, September 2026.
ABSTRACT Introduction Artificial intelligence (AI) is a branch of technology enabling machines to emulate complex human skills; it can also entail problem‐solving using bioinspired methods. It is used for automating systematic literature reviews (SLR), that is, defining a clinical question, locating relevant literature, preliminary screening, study ...
Ana M. Barragán, Sara Elena Ortiz Bonett, Eliana‐Isabel Rodríguez‐Grande, Alvaro David Orjuela‐Cañón, Oscar J. Perdomo, Guillermo Sánchez‐Vanegas   +5 more
wiley   +1 more source

Optimization of antibody binding by adjusting thermodynamic stability during the maturation of antibody affinities

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Somatic mutations and antibody clone selection occur in B‐cell hyper‐evolution over extremely brief periods of time. Herein, we developed a technique for antibody screening by immunizing alpacas with antigens and observing antibody sequence transitions over time, a method we named Tracking the Evolution of Antibodies over time.
Yoko Akazawa‐Ogawa, Tomonari Matsuda, Norihiko Kiyose, Nobuo Miyazaki, Tetsuo Fukuta, Motoyasu Adachi, Yuji Ito, Yoshihisa Hagihara   +7 more
wiley   +1 more source

Pairing Alpaca and Llama-Derived Single Domain Antibodies to Enhance Immunoassays for Ricin

Antibodies, 2017
Previously, our group isolated and evaluated anti-ricin single domain antibodies (sdAbs) derived from llamas, engineered them to further increase their thermal stability, and utilized them for the development of sensitive immunoassays. In work focused on
Kendrick B. Turner, Sabrina Hardy, Jinny L. Liu, Dan Zabetakis, P. Audrey Brozozog Lee, Ellen R. Goldman, George P. Anderson   +6 more
doaj   +1 more source

MAXTIA: A high‐throughput platform for rapid functional epitope mapping by kinetic screening of mutant libraries

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Accurate identification of epitope residues is essential for developing biopharmaceuticals and understanding the mechanisms of immune recognition. However, experimental approaches for residue‐level epitope mapping remain time‐consuming and labor‐intensive, while accurate computational prediction of protein–protein interfaces remains ...
Kihoon Kim, Ryo Matsunaga, Takanori Yokoo, Makoto Nakakido, Kouhei Tsumoto   +4 more
wiley   +1 more source

Gene expression profile in white alpaca (Vicugna pacos) skin

Animal, 2011
A cDNA library from white alpaca (Vicugna pacos) skin was constructed using SMART technology to investigate the global gene expression profile in alpaca skin and identify genes associated with physiology of alpaca skin and pigmentation.
R. Fan, Y. Dong, J. Cao, R. Bai, Z. Zhu, P. Li, J. Zhang, X. He, L. Lü, J. Yao, M. Mondal, G.W. Smith, C. Dong   +12 more
doaj   +1 more source

Tissue‐Adhesive Fabric‐Based Bioelectronics for Wearable and Implantable Applications

Advanced Functional Materials, Volume 36, Issue 66, 17 August 2026.
An implantable and wearable bioelectronic textile (iTextile) is introduced as a unified platform bridging wearable and implantable systems. By integrating a self‐healing polymer, stretchable silk fabric, conductive composite electrodes, and an adhesive hydrogel, the platform enables conformal, stable interfacing with soft tissues. The iTextile supports
Soojung An, Yewon Kim, Kyoungryong Kim, Heewon Choi, Sungjun Yoon, Jaewon Ju, Mikyung Shin, Donghee Son   +7 more
wiley   +1 more source

Establishment of a monoclonal antibody PMab-225 against alpaca podoplanin for immunohistochemical analyses

Biochemistry and Biophysics Reports, 2019
Podoplanin (PDPN) is known as a lymphatic endothelial cell marker. Monoclonal antibodies (mAbs) against human, mouse, rat, rabbit, dog, cat, bovine, pig, and horse PDPN have been established in our previous studies.
Y. Kato, Yoshikazu Furusawa, S. Yamada, Shunsuke Itai, Junko Takei, M. Sano, M. Kaneko   +6 more
semanticscholar   +1 more source

Multivalent antibody‐based conjugates as new tools for tailored modulation of G protein–coupled receptors

British Journal of Pharmacology, Volume 183, Issue 16, Page 4512-4531, August 2026.
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley   +1 more source

Economic effects of disease outbreaks on U.S. salmonid farms

Journal of the World Aquaculture Society, Volume 57, Issue 4, August 2026.
Abstract The U.S. salmonid industry is the second‐largest finfish sector of U.S. aquaculture, contributing $886 million and more than 2000 jobs to the U.S. economy in 2022. The goal of this study was to develop an economic analysis of the impact of losses from disease outbreaks to the U.S. salmonid industry.
Carole Engle, Shraddha Hegde, Jonathan van Senten, Ganesh Kumar, Christine Ellis, Gary Fornshell   +5 more
wiley   +1 more source