Results 41 to 50 of about 36,873 (244)

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

open access: yesAdvanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun   +23 more
wiley   +1 more source

Expression and localization of nerve growth factor (NGF) in the testis of alpaca <i>(llama pacos)</i>

open access: yesFolia Histochemica et Cytobiologica, 2011
During alpaca testis development and spermatogenesis, nerve growth factor (NGF) may play an important role. The main aim of this study was to determine the expression and localization of NGF in the alpaca testis, and to discuss the important role of NGF ...
Changsheng Dong   +4 more
doaj   +1 more source

Thrombotic Endocarditis in 10 Alpacas [PDF]

open access: yesJournal of Veterinary Internal Medicine, 2008
Background:A description of the clinical signs and necropsy findings in 10 alpacas with thrombotic endocarditis.Animals:Clinical cases admitted to 2 veterinary referral hospitals between May 1998 and December 2006.Methods:A retrospective study was performed by searching hospital records to identify alpacas diagnosed with endocarditis.Results:Common ...
A M, Firshman   +9 more
openaire   +2 more sources

Beyond mammals: the evolution of chewing and other forms of oropharyngeal food processing in vertebrates

open access: yesBiological Reviews, EarlyView.
ABSTRACT Oropharyngeal food processing exhibits a remarkable diversity among vertebrates, reflecting the evolution of specialised ‘processing centres’ associated with the mandibular, hyoid, and branchial arches. Although studies have detailed various food‐processing strategies and mechanisms across vertebrates, a coherent and comprehensive terminology ...
Daniel Schwarz   +6 more
wiley   +1 more source

Evaluation of SNP Genotyping in Alpacas Using the Bovine HD Genotyping Beadchip

open access: yesFrontiers in Genetics, 2019
Alpacas are one of four South American Camelid species living in the highlands of the Andes. Production of alpaca fiber contributes to the economy of the region and the livelihood of many rural families.
Manuel More   +4 more
doaj   +1 more source

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

open access: yesiNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng   +3 more
wiley   +1 more source

Malignant Neoplasia in Four Alpacas [PDF]

open access: yesJournal of Veterinary Diagnostic Investigation, 2004
Malignant neoplasia in 4 alpacas was characterized by acute onset of clinical signs and rapidly deteriorating condition. Postmortem examination revealed metastatic or multicentric neoplasia in the abdominal organs of alpacas 1, 3, and 4 and an extensive thoracic mass in alpaca 2.
Eva A, Sartin   +5 more
openaire   +2 more sources

Effects of bleaching and dyeing on the quality of alpaca tops and yarns

open access: yes, 2004
This paper reports the effects of bleaching of alpaca tops and dyeing of bleached alpaca tops/yarns on the quality of tops and yarns. A dark brown alpaca top was bleached with hydrogen peroxide. Two bleaching methods were tried for effectiveness of color
Christopher J. Hurren   +8 more
core   +1 more source

Evaluation of a non‐radioactive rapid test for determination of serum progesterone in South American camelids

open access: yesVeterinary Record, EarlyView.
Abstract Background Determination of the serum progesterone (P4) concentration is of high importance in reproductive medicine and may be applied for diagnosing pregnancy in South American camelids. P4 measurements in alpacas and llamas are usually performed using immunoassays, which are time consuming and require appropriate expertise of laboratory ...
Lina Längerer   +5 more
wiley   +1 more source

Turduckening black holes: an analytical and computational study [PDF]

open access: yes, 2009
We provide a detailed analysis of several aspects of the turduckening technique for evolving black holes. At the analytical level we study the constraint propagation for a general family of BSSN-type formulation of Einstein's field equations and identify
Brown, David   +4 more
core   +3 more sources

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